Cargando…

MiR-205 Is Progressively Down-Regulated in Lymph Node Metastasis but Fails as a Prognostic Biomarker in High-Risk Prostate Cancer

The treatment of high-risk prostate cancer (HRPCa) is a tremendous challenge for uro-oncologists. The identification of predictive moleculobiological markers allowing risk assessment of lymph node metastasis and systemic progression is essential in establishing effective treatment. In the current st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kalogirou, Charis, Spahn, Martin, Krebs, Markus, Joniau, Steven, Lerut, Evelyne, Burger, Maximilian, Scholz, Claus-Jürgen, Kneitz, Susanne, Riedmiller, Hubertus, Kneitz, Burkhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856012/ https://www.ncbi.nlm.nih.gov/pubmed/24173237 http://dx.doi.org/10.3390/ijms141121414

Ejemplares similares

Impact of miR-21, miR-126 and miR-221 as Prognostic Factors of Clear Cell Renal Cell Carcinoma with Tumor Thrombus of the Inferior Vena Cava
por: Vergho, Daniel Claudius, et al.
Publicado: (2014)

Distinct microRNA Expression Profile in Prostate Cancer Patients with Early Clinical Failure and the Impact of let-7 as Prognostic Marker in High-Risk Prostate Cancer
por: Schubert, Maria, et al.
Publicado: (2013)

Combination of expression levels of miR-21 and miR-126 is associated with cancer-specific survival in clear-cell renal cell carcinoma
por: Vergho, Daniel, et al.
Publicado: (2014)

miR-221-5p regulates proliferation and migration in human prostate cancer cells and reduces tumor growth in vivo
por: Kiener, Mirjam, et al.
Publicado: (2019)

miR-221 Augments TRAIL-Mediated Apoptosis in Prostate Cancer Cells by Inducing Endogenous TRAIL Expression and Targeting the Functional Repressors SOCS3 and PIK3R1
por: Krebs, Markus, et al.
Publicado: (2019)

miR-221-3p Regulates VEGFR2 Expression in High-Risk Prostate Cancer and Represents an Escape Mechanism from Sunitinib In Vitro
por: Krebs, Markus, et al.
Publicado: (2020)

Critical Evaluation of a microRNA-Based Risk Classifier Predicting Cancer-Specific Survival in Renal Cell Carcinoma with Tumor Thrombus of the Inferior Vena Cava
por: Kotlyar, Mischa J., et al.
Publicado: (2023)

DNA Methylation-Guided Prediction of Clinical Failure in High-Risk Prostate Cancer
por: Litovkin, Kirill, et al.
Publicado: (2015)

High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer
por: Eckhardt, Carolin, et al.
Publicado: (2021)

Identification of miR-21-5p and miR-210-3p serum levels as biomarkers for patients with papillary renal cell carcinoma: a multicenter analysis
por: Kalogirou, Charis, et al.
Publicado: (2020)

Relaxed imprinting of IGF2 in peripheral blood cells of patients with a history of prostate cancer
por: Belharazem, Djeda, et al.
Publicado: (2012)

An Anti-Ubiquitin Antibody Response in Transitional Cell Carcinoma of the Urinary Bladder
por: Ardelt, Peter U., et al.
Publicado: (2015)

MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer
por: Kalogirou, C., et al.
Publicado: (2021)

Impact of Lymph Node Burden on Survival of High-risk Prostate Cancer Patients Following Radical Prostatectomy and Pelvic Lymph Node Dissection
por: Moris, Lisa, et al.
Publicado: (2016)

The Role of Adjuvant Hormonal Treatment after Surgery for Localized High-Risk Prostate Cancer: Results of a Matched Multiinstitutional Analysis
por: Schubert, Maria, et al.
Publicado: (2012)

Persistent painless hemospermia due to metastatic melanoma of the right seminal vesicle
por: Papoutsoglou, Nikolaos, et al.
Publicado: (2013)

Sense and Nonsense of an Extended Pelvic Lymph Node Dissection in Prostate Cancer
por: Van Baelen, Anthony, et al.
Publicado: (2012)

Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration
por: Hailer, Amelie, et al.
Publicado: (2014)

A Giant Mucinous Adenocarcinoma Arising within a Villous Adenoma of the Urachus: Case Report and Review of the Literature
por: Joniau, Steven, et al.
Publicado: (2009)

Tumor thrombus of inferior vena cava in patients with renal cell carcinoma – clinical and oncological outcome of 50 patients after surgery
por: Vergho, Daniel Claudius, et al.
Publicado: (2012)

Overexpression of microRNA-205 predicts lymph node metastasis and indicates an unfavorable prognosis in endometrial cancer
por: Ma, Yong-Jing, et al.
Publicado: (2016)

Somatic Hypermutation in Muts Homologue (Msh)3-, Msh6-, and Msh3/Msh6-Deficient Mice Reveals a Role for the Msh2–Msh6 Heterodimer in Modulating the Base Substitution Pattern
por: Wiesendanger, Margrit, et al.
Publicado: (2000)

DNA Methylation Mediated Control of Gene Expression Is Critical for Development of Crown Gall Tumors
por: Gohlke, Jochen, et al.
Publicado: (2013)

Angiogenesis as Therapeutic Target in Metastatic Prostate Cancer – Narrowing the Gap Between Bench and Bedside
por: Solimando, Antonio Giovanni, et al.
Publicado: (2022)

Mucin-Poor Mucinous Tubular and Spindle Cell Carcinoma of the Kidney Presented with Multiple Metastases Two Years after Nephrectomy: An Atypical Behaviour of a Rare, Indolent Tumour
por: Sokolakis, I., et al.
Publicado: (2017)

Spine Fractures in Ankylosing Diseases: Recommendations of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU)
por: Reinhold, Maximilian, et al.
Publicado: (2018)

Clinical factors associated with failed sentinel lymph node mapping in endometrial cancer
por: Garrett, Alison A., et al.
Publicado: (2022)

Infektionsprophylaxe bei rheumatologischen Erkrankungen
por: Kneitz, Christian, et al.
Publicado: (2020)

Renal Cell Carcinoma with Synchronous Metastasis to the Calcaneus and Metachronous Metastases to the Ovary and Gallbladder
por: Decoene, Jasper, et al.
Publicado: (2011)

The Interleukin 2 Receptor α Chain/CD25 Promoter Is a Target for Nuclear Factor of Activated T Cells
por: Schuh, Kai, et al.
Publicado: (1998)

Wichtigste Impfungen bei Patienten mit rheumatologischen Erkrankungen und warum
por: Kneitz, C., et al.
Publicado: (2020)

miR-205 and miR-200c: Predictive Micro RNAs for Lymph Node Metastasis in Triple Negative Breast Cancer
por: Berber, Ufuk, et al.
Publicado: (2014)

Low frequency of p16(INK4a) promoter methylation in mammary carcinomas as revealed by positive display of methylated sites
por: Lilischkis, R, et al.
Publicado: (2000)

CD10-Positive Cutaneous PEComa: An Extremely Rare Skin Tumour
por: Ueberschaar, Simon, et al.
Publicado: (2020)

Technetium Tc 99m tilmanocept fails to detect sentinel lymph nodes in endometrial cancer
por: Reddy, Ravali A., et al.
Publicado: (2022)

The Genomic Landscape of Prostate Cancer
por: Spans, Lien, et al.
Publicado: (2013)

Ki-67, topoisomerase IIα and miR-221 have a limited prostate cancer risk stratification ability on a medium-term follow-up: results of a high-risk radical prostatectomy cohort
por: Marra, Giancarlo, et al.
Publicado: (2022)

Blood Vessel Density in Basal Cell Carcinomas and Benign Trichogenic Tumors as a Marker for Differential Diagnosis in Dermatopathology
por: Winter, Julia, et al.
Publicado: (2011)

Dermpath & Clinic: Where the shoe pinches — painful plantar plaque
por: Frings, Verena G., et al.
Publicado: (2020)

Mdm2-SNP309 polymorphism in prostate cancer: no evidence for association with increased risk or histopathological tumour characteristics
por: Stoehr, R, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_62o4pqh8dt0t0b2vl3pjuvmr2r