Protective Roles of Gadd45 and MDM2 in Blueberry Anthocyanins Mediated DNA Repair of Fragmented and Non-Fragmented DNA Damage in UV-Irradiated HepG2 Cells

Growth Arrest and DNA Damage-inducible 45 (Gadd45) and MDM2 proteins, together with p21 and p53, play important roles in cell cycle checkpoints, DNA repair, and genome integrity maintenance. Gadd45 and MDM2 were activated and transcribed instantly by UV irradiation, whereas blueberry anthocyanins (B...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Lu, Xiangyi, He, Guangyang, Gao, Xiang, Xu, Maonian, Zhang, Jingkai, Li, Meiling, Wang, Lifeng, Li, Zhenjing, Wang, Likui, Luo, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856014/
https://www.ncbi.nlm.nih.gov/pubmed/24177565
http://dx.doi.org/10.3390/ijms141121447

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