Cargando…
Association of Metabolic Syndrome and Albuminuria with Cardiovascular Risk in Occupational Drivers
BACKGROUND AND AIM: Metabolic syndrome (MetS) and albuminuria increase cardiovascular risk. However, in occupational drivers, the clinical significance of albuminuria and its association with MetS remain unclear. We investigated the prevalence of MetS, albuminuria and cardiovascular risk, and its as...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856047/ https://www.ncbi.nlm.nih.gov/pubmed/24201129 http://dx.doi.org/10.3390/ijms141121997 |
_version_ | 1782295007378538496 |
---|---|
author | Chen, Szu-Chia Chang, Jer-Ming Lin, Ming-Yen Hou, Meng-Ling Tsai, Jer-Chia Hwang, Shang-Jyh Chen, Hung-Chun |
author_facet | Chen, Szu-Chia Chang, Jer-Ming Lin, Ming-Yen Hou, Meng-Ling Tsai, Jer-Chia Hwang, Shang-Jyh Chen, Hung-Chun |
author_sort | Chen, Szu-Chia |
collection | PubMed |
description | BACKGROUND AND AIM: Metabolic syndrome (MetS) and albuminuria increase cardiovascular risk. However, in occupational drivers, the clinical significance of albuminuria and its association with MetS remain unclear. We investigated the prevalence of MetS, albuminuria and cardiovascular risk, and its associated risk factors in occupational drivers; METHODS: 441 occupational drivers and 432 age- and sex-stratified matched counterpart controls were enrolled. MetS was defined using Adult Treatment Panel III for Asians. Albuminuria was defined as urine albumin-to-creatinine ratio ≥ 30 mg/g. Cardiovascular disease risk was evaluated by Framingham Risk Score (FRS); RESULTS: A significantly higher prevalence of MetS (43.1% vs. 25.5%, p < 0.001), albuminuria (12.0% vs. 5.6%, p = 0.001) and high FRS risk ≥ 10% of 10-year risk (46.9% vs. 35.2%, p < 0.001) was found in occupational drivers compared with their counterpart controls. Multiple logistic regression analysis showed that old age, a history of diabetes, gout and betel nut chewing, less exercise and albuminuria (odds ratio [OR], 2.75; p = 0.01) were risk factors for MetS, while a history of renal disease, diabetes and hypertension, and MetS (OR, 2.28; p = 0.01) were risk factors for albuminuria in occupational drivers; CONCLUSIONS: Our study demonstrated that MetS and albuminuria were public health problems in occupational drivers. An education program for promoting healthy lifestyle and a regular occupational health visit for early detection and interventions should be established. |
format | Online Article Text |
id | pubmed-3856047 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-38560472013-12-09 Association of Metabolic Syndrome and Albuminuria with Cardiovascular Risk in Occupational Drivers Chen, Szu-Chia Chang, Jer-Ming Lin, Ming-Yen Hou, Meng-Ling Tsai, Jer-Chia Hwang, Shang-Jyh Chen, Hung-Chun Int J Mol Sci Article BACKGROUND AND AIM: Metabolic syndrome (MetS) and albuminuria increase cardiovascular risk. However, in occupational drivers, the clinical significance of albuminuria and its association with MetS remain unclear. We investigated the prevalence of MetS, albuminuria and cardiovascular risk, and its associated risk factors in occupational drivers; METHODS: 441 occupational drivers and 432 age- and sex-stratified matched counterpart controls were enrolled. MetS was defined using Adult Treatment Panel III for Asians. Albuminuria was defined as urine albumin-to-creatinine ratio ≥ 30 mg/g. Cardiovascular disease risk was evaluated by Framingham Risk Score (FRS); RESULTS: A significantly higher prevalence of MetS (43.1% vs. 25.5%, p < 0.001), albuminuria (12.0% vs. 5.6%, p = 0.001) and high FRS risk ≥ 10% of 10-year risk (46.9% vs. 35.2%, p < 0.001) was found in occupational drivers compared with their counterpart controls. Multiple logistic regression analysis showed that old age, a history of diabetes, gout and betel nut chewing, less exercise and albuminuria (odds ratio [OR], 2.75; p = 0.01) were risk factors for MetS, while a history of renal disease, diabetes and hypertension, and MetS (OR, 2.28; p = 0.01) were risk factors for albuminuria in occupational drivers; CONCLUSIONS: Our study demonstrated that MetS and albuminuria were public health problems in occupational drivers. An education program for promoting healthy lifestyle and a regular occupational health visit for early detection and interventions should be established. Molecular Diversity Preservation International (MDPI) 2013-11-06 /pmc/articles/PMC3856047/ /pubmed/24201129 http://dx.doi.org/10.3390/ijms141121997 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Chen, Szu-Chia Chang, Jer-Ming Lin, Ming-Yen Hou, Meng-Ling Tsai, Jer-Chia Hwang, Shang-Jyh Chen, Hung-Chun Association of Metabolic Syndrome and Albuminuria with Cardiovascular Risk in Occupational Drivers |
title | Association of Metabolic Syndrome and Albuminuria with Cardiovascular Risk in Occupational Drivers |
title_full | Association of Metabolic Syndrome and Albuminuria with Cardiovascular Risk in Occupational Drivers |
title_fullStr | Association of Metabolic Syndrome and Albuminuria with Cardiovascular Risk in Occupational Drivers |
title_full_unstemmed | Association of Metabolic Syndrome and Albuminuria with Cardiovascular Risk in Occupational Drivers |
title_short | Association of Metabolic Syndrome and Albuminuria with Cardiovascular Risk in Occupational Drivers |
title_sort | association of metabolic syndrome and albuminuria with cardiovascular risk in occupational drivers |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856047/ https://www.ncbi.nlm.nih.gov/pubmed/24201129 http://dx.doi.org/10.3390/ijms141121997 |
work_keys_str_mv | AT chenszuchia associationofmetabolicsyndromeandalbuminuriawithcardiovascularriskinoccupationaldrivers AT changjerming associationofmetabolicsyndromeandalbuminuriawithcardiovascularriskinoccupationaldrivers AT linmingyen associationofmetabolicsyndromeandalbuminuriawithcardiovascularriskinoccupationaldrivers AT houmengling associationofmetabolicsyndromeandalbuminuriawithcardiovascularriskinoccupationaldrivers AT tsaijerchia associationofmetabolicsyndromeandalbuminuriawithcardiovascularriskinoccupationaldrivers AT hwangshangjyh associationofmetabolicsyndromeandalbuminuriawithcardiovascularriskinoccupationaldrivers AT chenhungchun associationofmetabolicsyndromeandalbuminuriawithcardiovascularriskinoccupationaldrivers |