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Ionizing Radiation-Induced Responses in Human Cells with Differing TP53 Status

Ionizing radiation triggers diverse responses in human cells encompassing apoptosis, necrosis, stress-induced premature senescence (SIPS), autophagy, and endopolyploidy (e.g., multinucleation). Most of these responses result in loss of colony-forming ability in the clonogenic survival assay. However...

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Detalles Bibliográficos
Autores principales: Mirzayans, Razmik, Andrais, Bonnie, Scott, April, Wang, Ying W., Murray, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856071/
https://www.ncbi.nlm.nih.gov/pubmed/24232458
http://dx.doi.org/10.3390/ijms141122409