Cargando…
Ionizing Radiation-Induced Responses in Human Cells with Differing TP53 Status
Ionizing radiation triggers diverse responses in human cells encompassing apoptosis, necrosis, stress-induced premature senescence (SIPS), autophagy, and endopolyploidy (e.g., multinucleation). Most of these responses result in loss of colony-forming ability in the clonogenic survival assay. However...
Autores principales: | Mirzayans, Razmik, Andrais, Bonnie, Scott, April, Wang, Ying W., Murray, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856071/ https://www.ncbi.nlm.nih.gov/pubmed/24232458 http://dx.doi.org/10.3390/ijms141122409 |
Ejemplares similares
-
Multinucleated Giant Cancer Cells Produced in Response to Ionizing Radiation Retain Viability and Replicate Their Genome
por: Mirzayans, Razmik, et al.
Publicado: (2017) -
New Insights into p53 Signaling and Cancer Cell Response to DNA Damage: Implications for Cancer Therapy
por: Mirzayans, Razmik, et al.
Publicado: (2012) -
Role of p16(INK4A) in Replicative Senescence and DNA Damage-Induced Premature Senescence in p53-Deficient Human Cells
por: Mirzayans, Razmik, et al.
Publicado: (2012) -
Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome
por: Mirzayans, Razmik, et al.
Publicado: (2017) -
Do Multiwell Plate High Throughput Assays Measure Loss of Cell Viability Following Exposure to Genotoxic Agents?
por: Mirzayans, Razmik, et al.
Publicado: (2017)