ADAR Enzyme and miRNA Story: A Nucleotide that Can Make the Difference

Adenosine deaminase acting on RNA (ADAR) enzymes convert adenosine (A) to inosine (I) in double-stranded (ds) RNAs. Since Inosine is read as Guanosine, the biological consequence of ADAR enzyme activity is an A/G conversion within RNA molecules. A-to-I editing events can occur on both coding and non...

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Detalles Bibliográficos
Autores principales: Tomaselli, Sara, Bonamassa, Barbara, Alisi, Anna, Nobili, Valerio, Locatelli, Franco, Gallo, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856091/
https://www.ncbi.nlm.nih.gov/pubmed/24256817
http://dx.doi.org/10.3390/ijms141122796

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