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Gastric Outlet Obstruction Due to Gastric Amyloidosis Mimicking Malignancy in a Patient with Ankylosing Spondylitis

Amyloidosis is a group of disorders characterized by the extracellular accumulation of insoluble, fibrillar proteins in various organs and tissues. It is classified, on the basis of the identity of the precursor protein, as primary, secondary, or familial amyloidosis. Gastrointestinal amyloidosis us...

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Autores principales: Seon, Choon Sik, Park, Young Sook, Jung, Yu Min, Choi, Jeong Ho, Son, Byoung Kwan, Ahn, Sang Bong, Kim, Seong Hwan, Jo, Yun Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Gastrointestinal Endoscopy 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856268/
https://www.ncbi.nlm.nih.gov/pubmed/24340260
http://dx.doi.org/10.5946/ce.2013.46.6.651
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author Seon, Choon Sik
Park, Young Sook
Jung, Yu Min
Choi, Jeong Ho
Son, Byoung Kwan
Ahn, Sang Bong
Kim, Seong Hwan
Jo, Yun Ju
author_facet Seon, Choon Sik
Park, Young Sook
Jung, Yu Min
Choi, Jeong Ho
Son, Byoung Kwan
Ahn, Sang Bong
Kim, Seong Hwan
Jo, Yun Ju
author_sort Seon, Choon Sik
collection PubMed
description Amyloidosis is a group of disorders characterized by the extracellular accumulation of insoluble, fibrillar proteins in various organs and tissues. It is classified, on the basis of the identity of the precursor protein, as primary, secondary, or familial amyloidosis. Gastrointestinal amyloidosis usually presents as bleeding, ulceration, malabsorption, protein loss, and diarrhea. However, gastric amyloidosis with gastric outlet obstruction mimicking linitis plastica is rare. We report a case of gastrointestinal amyloidosis with gastric outlet obstruction in a patient with ankylosing spondylitis. The patient was indicated for subtotal gastrectomy because of the aggravation of obstructive symptoms, but refused the operation and was transferred to another hospital. Three months later, the patient died of aspiration pneumonia during medical treatment.
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spelling pubmed-38562682013-12-11 Gastric Outlet Obstruction Due to Gastric Amyloidosis Mimicking Malignancy in a Patient with Ankylosing Spondylitis Seon, Choon Sik Park, Young Sook Jung, Yu Min Choi, Jeong Ho Son, Byoung Kwan Ahn, Sang Bong Kim, Seong Hwan Jo, Yun Ju Clin Endosc Case Report Amyloidosis is a group of disorders characterized by the extracellular accumulation of insoluble, fibrillar proteins in various organs and tissues. It is classified, on the basis of the identity of the precursor protein, as primary, secondary, or familial amyloidosis. Gastrointestinal amyloidosis usually presents as bleeding, ulceration, malabsorption, protein loss, and diarrhea. However, gastric amyloidosis with gastric outlet obstruction mimicking linitis plastica is rare. We report a case of gastrointestinal amyloidosis with gastric outlet obstruction in a patient with ankylosing spondylitis. The patient was indicated for subtotal gastrectomy because of the aggravation of obstructive symptoms, but refused the operation and was transferred to another hospital. Three months later, the patient died of aspiration pneumonia during medical treatment. The Korean Society of Gastrointestinal Endoscopy 2013-11 2013-11-19 /pmc/articles/PMC3856268/ /pubmed/24340260 http://dx.doi.org/10.5946/ce.2013.46.6.651 Text en Copyright © 2013 Korean Society of Gastrointestinal Endoscopy http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Seon, Choon Sik
Park, Young Sook
Jung, Yu Min
Choi, Jeong Ho
Son, Byoung Kwan
Ahn, Sang Bong
Kim, Seong Hwan
Jo, Yun Ju
Gastric Outlet Obstruction Due to Gastric Amyloidosis Mimicking Malignancy in a Patient with Ankylosing Spondylitis
title Gastric Outlet Obstruction Due to Gastric Amyloidosis Mimicking Malignancy in a Patient with Ankylosing Spondylitis
title_full Gastric Outlet Obstruction Due to Gastric Amyloidosis Mimicking Malignancy in a Patient with Ankylosing Spondylitis
title_fullStr Gastric Outlet Obstruction Due to Gastric Amyloidosis Mimicking Malignancy in a Patient with Ankylosing Spondylitis
title_full_unstemmed Gastric Outlet Obstruction Due to Gastric Amyloidosis Mimicking Malignancy in a Patient with Ankylosing Spondylitis
title_short Gastric Outlet Obstruction Due to Gastric Amyloidosis Mimicking Malignancy in a Patient with Ankylosing Spondylitis
title_sort gastric outlet obstruction due to gastric amyloidosis mimicking malignancy in a patient with ankylosing spondylitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856268/
https://www.ncbi.nlm.nih.gov/pubmed/24340260
http://dx.doi.org/10.5946/ce.2013.46.6.651
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