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Analysis of protein coding mutations in hiPSCs and their possible role during somatic cell reprogramming
Recent studies indicate that human induced pluripotent stem cells (hiPSCs) contain genomic structural variations and point mutations in coding regions. However, these studies have focused on fibroblast-derived hiPSCs, and it is currently unknown whether the use of alternative somatic cell sources wi...
Autores principales: | Ruiz, Sergio, Gore, Athurva, Li, Zhe, Panopoulos, Athanasia D., Montserrat, Nuria, Fung, Ho-Lim, Giorgetti, Alessandra, Bilic, Josipa, Batchelder, Erika M., Zaehres, Holm, Schöler, Hans R., Zhang, Kun, Belmonte, Juan Carlos Izpisua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856317/ https://www.ncbi.nlm.nih.gov/pubmed/23340422 http://dx.doi.org/10.1038/ncomms2381 |
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