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Identification of Hypermethylation in Hepatocyte Cell Adhesion Molecule Gene Promoter Region in Bladder Carcinoma

Background: Epigenetic regulation such as aberrant hypermethylation of CpG islands in promoter plays a key role in tumorigenesis. 5-Aza-2'-deoxycytidine (5-aza-CdR) which is a potent inhibitor of DNA methylation can reverse the abnormal hypermethylation of the silenced tumor suppressor genes (T...

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Detalles Bibliográficos
Autores principales:	Tao, Jia, Liu, Qi, Wu, Xiaohou, Xu, Xin, Zhang, Yanyi, Wang, Qiuju, Luo, Chunli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856376/ https://www.ncbi.nlm.nih.gov/pubmed/24324362 http://dx.doi.org/10.7150/ijms.6460

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