Development of Hematopoietic Stem Cell Based Gene Therapy for HIV-1 Infection: Considerations for Proof of Concept Studies and Translation to Standard Medical Practice

Over the past 15 years we have been investigating an alternative approach to treating HIV-1/AIDS, based on the creation of a disease-resistant immune system through transplantation of autologous, gene-modified (HIV-1-resistant) hematopoietic stem and progenitor cells (GM-HSPC). We propose that the e...

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Detalles Bibliográficos
Autores principales: DiGiusto, David L., Stan, Rodica, Krishnan, Amrita, Li, Haitang, Rossi, John J., Zaia, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856421/
https://www.ncbi.nlm.nih.gov/pubmed/24284880
http://dx.doi.org/10.3390/v5112898

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