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Protein Ser/Thr phosphatase-6 is required for maintenance of E-cadherin at adherens junctions
BACKGROUND: Epithelial tissues depend on intercellular homodimerization of E-cadherin and loss of E-cadherin is central to the epithelial to mesenchymal transition seen in multiple human diseases. Signaling pathways regulate E-cadherin function and cellular distribution via phosphorylation of the cy...
Autores principales: | Ohama, Takashi, Wang, Lifu, Griner, Erin M, Brautigan, David L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856536/ https://www.ncbi.nlm.nih.gov/pubmed/24063632 http://dx.doi.org/10.1186/1471-2121-14-42 |
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