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The favorable kinetics and balance of nebivolol-stimulated nitric oxide and peroxynitrite release in human endothelial cells

BACKGROUND: Nebivolol is a third-generation beta-blocker used to treat hypertension. The vasodilation properties of nebivolol have been attributed to nitric oxide (NO) release. However, the kinetics and mechanism of nebivolol-stimulated bioavailable NO are not fully understood. METHODS: Using ampero...

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Detalles Bibliográficos
Autores principales: Mason, R Preston, Jacob, Robert F, Corbalan, J Jose, Szczesny, Damian, Matysiak, Kinga, Malinski, Tadeusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856588/
https://www.ncbi.nlm.nih.gov/pubmed/24074014
http://dx.doi.org/10.1186/2050-6511-14-48