Optimization and validation of a reversed-phase high performance liquid chromatography method for the measurement of bovine liver methylmalonyl-coenzyme a mutase activity

BACKGROUND: Methylmalonyl-CoA mutase (MCM) is an adenosylcobalamin-dependent enzyme that catalyses the interconversion of (2R)-methylmalonyl-CoA to succinyl-CoA. In humans, a deficit in activity of MCM, due to an impairment of intracellular formation of adenosylcobalamin and methylcobalamin results...

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Detalles Bibliográficos
Autores principales: Ouattara, Bazoumana, Duplessis, Mélissa, Girard, Christiane L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856599/
https://www.ncbi.nlm.nih.gov/pubmed/24131771
http://dx.doi.org/10.1186/1471-2091-14-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856599/
https://www.ncbi.nlm.nih.gov/pubmed/24131771
http://dx.doi.org/10.1186/1471-2091-14-25

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