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Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding

Cocrystal formation rates during dry grinding and liquid-assisted grinding were investigated by X-ray powder diffractometry and Raman spectroscopy. Two polymorphic forms of piracetam were used to prepare known piracetam cocrystals as model substances, i.e., piracetam-citric acid and piracetam-tartar...

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Detalles Bibliográficos
Autores principales: Rehder, Sönke, Klukkert, Marten, Löbmann, Korbinian A. M., Strachan, Clare J., Sakmann, Albrecht, Gordon, Keith, Rades, Thomas, Leopold, Claudia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857054/
https://www.ncbi.nlm.nih.gov/pubmed/24309304
http://dx.doi.org/10.3390/pharmaceutics3040706