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Infective Endocarditis Epidemiology Over Five Decades: A Systematic Review

AIMS: To Assess changes in infective endocarditis (IE) epidemiology over the last 5 decades. METHODS AND RESULTS: We searched the published literature using PubMed, MEDLINE, and EMBASE from inception until December 2011. DATA FROM: Einstein Medical Center, Philadelphia, PA were also included. Criter...

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Autores principales: Slipczuk, Leandro, Codolosa, J. Nicolas, Davila, Carlos D., Romero-Corral, Abel, Yun, Jeong, Pressman, Gregg S., Figueredo, Vincent M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857279/
https://www.ncbi.nlm.nih.gov/pubmed/24349331
http://dx.doi.org/10.1371/journal.pone.0082665
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author Slipczuk, Leandro
Codolosa, J. Nicolas
Davila, Carlos D.
Romero-Corral, Abel
Yun, Jeong
Pressman, Gregg S.
Figueredo, Vincent M.
author_facet Slipczuk, Leandro
Codolosa, J. Nicolas
Davila, Carlos D.
Romero-Corral, Abel
Yun, Jeong
Pressman, Gregg S.
Figueredo, Vincent M.
author_sort Slipczuk, Leandro
collection PubMed
description AIMS: To Assess changes in infective endocarditis (IE) epidemiology over the last 5 decades. METHODS AND RESULTS: We searched the published literature using PubMed, MEDLINE, and EMBASE from inception until December 2011. DATA FROM: Einstein Medical Center, Philadelphia, PA were also included. Criteria for inclusion in this systematic review included studies with reported IE microbiology, IE definition, description of population studied, and time frame. Two authors independently extracted data and assessed manuscript quality. One hundred sixty studies (27,083 patients) met inclusion criteria. Among hospital-based studies (n=142; 23,606 patients) staphylococcal IE percentage increased over time, with coagulase-negative staphylococcus (CNS) increasing over each of the last 5 decades (p<0.001) and Staphylococcus aureus (SA) in the last decade (21% to 30%; p<0.05). Streptococcus viridans (SV) and culture negative (CN) IE frequency decreased over time (p<0.001), while enterococcal IE increased in the last decade (p<0.01). Patient age and male predominance increased over time as well. In subgroup analysis, SA frequency increased in North America, but not the rest of the world. This was due, in part, to an increase in intravenous drug abuse IE in North America (p<0.001). Among population-based studies (n=18; 3,477 patients) no significant changes were found. CONCLUSION: Important changes occurred in IE epidemiology over the last half-century, especially in the last decade. Staphylococcal and enterococcal IE percentage increased while SV and CN IE decreased. Moreover, mean age at diagnosis increased together with male:female ratio. These changes should be considered at the time of decision-making in treatment of and prophylaxis for IE.
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spelling pubmed-38572792013-12-13 Infective Endocarditis Epidemiology Over Five Decades: A Systematic Review Slipczuk, Leandro Codolosa, J. Nicolas Davila, Carlos D. Romero-Corral, Abel Yun, Jeong Pressman, Gregg S. Figueredo, Vincent M. PLoS One Research Article AIMS: To Assess changes in infective endocarditis (IE) epidemiology over the last 5 decades. METHODS AND RESULTS: We searched the published literature using PubMed, MEDLINE, and EMBASE from inception until December 2011. DATA FROM: Einstein Medical Center, Philadelphia, PA were also included. Criteria for inclusion in this systematic review included studies with reported IE microbiology, IE definition, description of population studied, and time frame. Two authors independently extracted data and assessed manuscript quality. One hundred sixty studies (27,083 patients) met inclusion criteria. Among hospital-based studies (n=142; 23,606 patients) staphylococcal IE percentage increased over time, with coagulase-negative staphylococcus (CNS) increasing over each of the last 5 decades (p<0.001) and Staphylococcus aureus (SA) in the last decade (21% to 30%; p<0.05). Streptococcus viridans (SV) and culture negative (CN) IE frequency decreased over time (p<0.001), while enterococcal IE increased in the last decade (p<0.01). Patient age and male predominance increased over time as well. In subgroup analysis, SA frequency increased in North America, but not the rest of the world. This was due, in part, to an increase in intravenous drug abuse IE in North America (p<0.001). Among population-based studies (n=18; 3,477 patients) no significant changes were found. CONCLUSION: Important changes occurred in IE epidemiology over the last half-century, especially in the last decade. Staphylococcal and enterococcal IE percentage increased while SV and CN IE decreased. Moreover, mean age at diagnosis increased together with male:female ratio. These changes should be considered at the time of decision-making in treatment of and prophylaxis for IE. Public Library of Science 2013-12-09 /pmc/articles/PMC3857279/ /pubmed/24349331 http://dx.doi.org/10.1371/journal.pone.0082665 Text en © 2013 Slipczuk et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Slipczuk, Leandro
Codolosa, J. Nicolas
Davila, Carlos D.
Romero-Corral, Abel
Yun, Jeong
Pressman, Gregg S.
Figueredo, Vincent M.
Infective Endocarditis Epidemiology Over Five Decades: A Systematic Review
title Infective Endocarditis Epidemiology Over Five Decades: A Systematic Review
title_full Infective Endocarditis Epidemiology Over Five Decades: A Systematic Review
title_fullStr Infective Endocarditis Epidemiology Over Five Decades: A Systematic Review
title_full_unstemmed Infective Endocarditis Epidemiology Over Five Decades: A Systematic Review
title_short Infective Endocarditis Epidemiology Over Five Decades: A Systematic Review
title_sort infective endocarditis epidemiology over five decades: a systematic review
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857279/
https://www.ncbi.nlm.nih.gov/pubmed/24349331
http://dx.doi.org/10.1371/journal.pone.0082665
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