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Antitumor activity of an immunocytokine composed of an anti-GD2 antibody and the IL-15 superagonist RLI
The use of interleukin (IL)-15 or the IL-15 superagonist RLI as immunological adjuvants presents many advantages over that of IL-2, including a reduced toxicity and an improved efficacy. We have generated an immunocytokine that specifically targets RLI to a tumor-associated antigen, namely, disialog...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857326/ https://www.ncbi.nlm.nih.gov/pubmed/24349876 http://dx.doi.org/10.4161/onci.26441 |