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Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice

Intrauterine nutrition can program metabolism, creating stable changes in physiology that may have significant health consequences. The mechanism underlying these changes is widely assumed to involve epigenetic changes to the expression of metabolic genes, but evidence supporting this idea is limite...

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Detalles Bibliográficos
Autores principales: Li, Cheryl C.Y., Young, Paul E., Maloney, Christopher A., Eaton, Sally A., Cowley, Mark J., Buckland, Michael E, Preiss, Thomas, Henstridge, Darren C., Cooney, Gregory J., Febbraio, Mark A., Martin, David I.K., Cropley, Jennifer E., Suter, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857340/
https://www.ncbi.nlm.nih.gov/pubmed/23764993
http://dx.doi.org/10.4161/epi.24656