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Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice
Intrauterine nutrition can program metabolism, creating stable changes in physiology that may have significant health consequences. The mechanism underlying these changes is widely assumed to involve epigenetic changes to the expression of metabolic genes, but evidence supporting this idea is limite...
Autores principales: | Li, Cheryl C.Y., Young, Paul E., Maloney, Christopher A., Eaton, Sally A., Cowley, Mark J., Buckland, Michael E, Preiss, Thomas, Henstridge, Darren C., Cooney, Gregory J., Febbraio, Mark A., Martin, David I.K., Cropley, Jennifer E., Suter, Catherine M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857340/ https://www.ncbi.nlm.nih.gov/pubmed/23764993 http://dx.doi.org/10.4161/epi.24656 |
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