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FSGS3/CD2AP is a barbed-end capping protein that stabilizes actin and strengthens adherens junctions
By combining in vitro reconstitution biochemistry with a cross-linking approach, we have identified focal segmental glomerulosclerosis 3/CD2-associated protein (FSGS3/CD2AP) as a novel actin barbed-end capping protein responsible for actin stability at the adherens junction. FSGS3/CD2AP colocalizes...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857477/ https://www.ncbi.nlm.nih.gov/pubmed/24322428 http://dx.doi.org/10.1083/jcb.201304143 |