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FSGS3/CD2AP is a barbed-end capping protein that stabilizes actin and strengthens adherens junctions

By combining in vitro reconstitution biochemistry with a cross-linking approach, we have identified focal segmental glomerulosclerosis 3/CD2-associated protein (FSGS3/CD2AP) as a novel actin barbed-end capping protein responsible for actin stability at the adherens junction. FSGS3/CD2AP colocalizes...

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Detalles Bibliográficos
Autores principales: Tang, Vivian W., Brieher, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857477/
https://www.ncbi.nlm.nih.gov/pubmed/24322428
http://dx.doi.org/10.1083/jcb.201304143