Myelopoietic Efficacy of Orlistat in Murine Hosts Bearing T Cell Lymphoma: Implication in Macrophage Differentiation and Activation

Orlistat, an inhibitor of fatty acid synthase (FASN), acts as an antitumor agent by blocking de novo fatty acid synthesis of tumor cells. Although, myelopoiesis also depends on de novo fatty acid synthesis, the effect of orlistat on differentiation of macrophages, which play a central role in host’s...

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Detalles Bibliográficos
Autores principales: Kant, Shiva, Kumar, Ajay, Singh, Sukh Mahendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857782/
https://www.ncbi.nlm.nih.gov/pubmed/24349275
http://dx.doi.org/10.1371/journal.pone.0082396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857782/
https://www.ncbi.nlm.nih.gov/pubmed/24349275
http://dx.doi.org/10.1371/journal.pone.0082396

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