Human Fanconi Anemia Complementation Group A Protein Stimulates the 5’ Flap Endonuclease Activity of FEN1

In eukaryotic cells, Flap endonuclease 1 (FEN1) is a major structure-specific endonuclease that processes 5’ flapped structures during maturation of lagging strand DNA synthesis, long patch base excision repair, and rescue of stalled replication forks. Here we report that fanconi anemia complementat...

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Detalles Bibliográficos
Autores principales: Qian, Liangyue, Yuan, Fenghua, Rodriguez-Tello, Paola, Padgaonkar, Suyog, Zhang, Yanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857783/
https://www.ncbi.nlm.nih.gov/pubmed/24349332
http://dx.doi.org/10.1371/journal.pone.0082666

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