TNFα Signals via p66(Shc) to Induce E-Selectin, Promote Leukocyte Transmigration and Enhance Permeability in Human Endothelial Cells

Endothelial cells participate in inflammatory events leading to atherogenesis by regulating endothelial cell permeability via the expression of VE-Cadherin and β-catenin and leukocyte recruitment via the expression of E-Selectins and other adhesion molecules. The protein p66(Shc) acts as a sensor/in...

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Detalles Bibliográficos
Autores principales: Laviola, Luigi, Orlando, Maura Roberta, Incalza, Maria Angela, Caccioppoli, Cristina, Melchiorre, Mariangela, Leonardini, Anna, Cignarelli, Angelo, Tortosa, Federica, Labarbuta, Rossella, Martemucci, Sabina, Pacelli, Consiglia, Cocco, Tiziana, Perrini, Sebastio, Natalicchio, Annalisa, Giorgino, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857848/
https://www.ncbi.nlm.nih.gov/pubmed/24349153
http://dx.doi.org/10.1371/journal.pone.0081930

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