Cargando…

Extracellular microvesicles from astrocytes contain functional glutamate transporters: regulation by protein kinase C and cell activation

Glutamate transport through astrocytic excitatory amino-acid transporters (EAAT)-1 and EAAT-2 is paramount for neural homeostasis. EAAT-1 has been reported in secreted extracellular microvesicles (eMV, such as exosomes) and because the protein kinase C (PKC) family controls the sub-cellular distribu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gosselin, Romain-Daniel, Meylan, Patrick, Decosterd, Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857901/ https://www.ncbi.nlm.nih.gov/pubmed/24368897 http://dx.doi.org/10.3389/fncel.2013.00251

Ejemplares similares

Erythrocytic α-synuclein contained in microvesicles regulates astrocytic glutamate homeostasis: a new perspective on Parkinson’s disease pathogenesis
por: Sheng, Lifu, et al.
Publicado: (2020)

Low micromolar Ba(2+) potentiates glutamate transporter current in hippocampal astrocytes
por: Afzalov, Ramil, et al.
Publicado: (2013)

Tonic extracellular glutamate and ischaemia: glutamate antiporter system x(c) (−) regulates anoxic depolarization in hippocampus
por: Heit, Bradley S., et al.
Publicado: (2022)

Ghrelin Regulates Glucose and Glutamate Transporters in Hypothalamic Astrocytes
por: Fuente-Martín, Esther, et al.
Publicado: (2016)

The Regulation of Astrocytic Glutamate Transporters in Health and Neurodegenerative Diseases
por: Todd, Alison C., et al.
Publicado: (2020)

Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation
por: Brites, Dora, et al.
Publicado: (2015)

Functional changes in glutamate transporters and astrocyte biophysical properties in a rodent model of focal cortical dysplasia
por: Campbell, Susan L., et al.
Publicado: (2014)

Astrocytic Glutamate Transporter 1 (GLT1) Deficiency Reduces Anxiety- and Depression-Like Behaviors in Mice
por: Jia, Yun-Fang, et al.
Publicado: (2020)

Activation of Astrocytic μ-opioid Receptor Elicits Fast Glutamate Release Through TREK-1-Containing K2P Channel in Hippocampal Astrocytes
por: Woo, Dong Ho, et al.
Publicado: (2018)

Inositol hexakisphosphate kinases differentially regulate trafficking of vesicular glutamate transporters 1 and 2
por: Li, Haiyan, et al.
Publicado: (2022)

Inhibition of the Mitochondrial Glutamate Carrier SLC25A22 in Astrocytes Leads to Intracellular Glutamate Accumulation
por: Goubert, Emmanuelle, et al.
Publicado: (2017)

Cerebrospinal Fluid of Patients With Alzheimer’s Disease Contains Increased Percentages of Synaptophysin-Bearing Microvesicles
por: Utz, Janine, et al.
Publicado: (2021)

Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes
por: Zhang, Haijun, et al.
Publicado: (2009)

Aquaporin 4-Mediated Glutamate-Induced Astrocyte Swelling Is Partially Mediated through Metabotropic Glutamate Receptor 5 Activation
por: Shi, Zhongfang, et al.
Publicado: (2017)

Regulation of Glutamate, GABA and Dopamine Transporter Uptake, Surface Mobility and Expression
por: Ryan, Renae M., et al.
Publicado: (2021)

Extracellular Monomeric Tau Is Internalized by Astrocytes
por: Perea, Juan Ramón, et al.
Publicado: (2019)

Ketamine Within Clinically Effective Range Inhibits Glutamate Transmission From Astrocytes to Neurons and Disrupts Synchronization of Astrocytic SICs
por: Zhang, Yu, et al.
Publicado: (2019)

Astrocytic Regulation of Glutamate Transmission in Schizophrenia
por: Mei, Yu-Ying, et al.
Publicado: (2018)

L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the ‘collusion’ hypothesis for increased extracellular L-glutamate concentration in neuroinflammation
por: Takaki, Junpei, et al.
Publicado: (2012)

Microvesicles: What is the Role in Multiple Sclerosis?
por: Carandini, Tiziana, et al.
Publicado: (2015)

Acquisition and expression of conditioned taste aversion differentially affects extracellular signal regulated kinase and glutamate receptor phosphorylation in rat prefrontal cortex and nucleus accumbens
por: Marotta, Roberto, et al.
Publicado: (2014)

Disruption of the Glutamate–Glutamine Cycle Involving Astrocytes in an Animal Model of Depression for Males and Females
por: Rappeneau, Virginie, et al.
Publicado: (2016)

Glutamate transporters: The arrestin connection
por: Zafra, Francisco, et al.
Publicado: (2016)

Distribution of vesicular glutamate transporters in the human brain
por: Vigneault, Érika, et al.
Publicado: (2015)

Control of Long-Term Plasticity by Glutamate Transporters
por: Valtcheva, Silvana, et al.
Publicado: (2019)

Rapid recycling of glutamate transporters on the astroglial surface
por: Michaluk, Piotr, et al.
Publicado: (2021)

The Effect of GLT-1 Upregulation on Extracellular Glutamate Dynamics
por: Wilkie, Crystal M., et al.
Publicado: (2021)

Extracellular vesicles: Exosomes, microvesicles, and friends
por: Raposo, Graça, et al.
Publicado: (2013)

Infrared Nanospectroscopy of Individual Extracellular Microvesicles
por: Polito, Raffaella, et al.
Publicado: (2021)

A Computational Model to Investigate Astrocytic Glutamate Uptake Influence on Synaptic Transmission and Neuronal Spiking
por: Allam, Sushmita L., et al.
Publicado: (2012)

Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype
por: Zimmer, Eduardo R., et al.
Publicado: (2015)

Extracellular Electrophysiological Measurements of Cooperative Signals in Astrocytes Populations
por: Mestre, Ana L. G., et al.
Publicado: (2017)

Laser-scanning astrocyte mapping reveals increased glutamate-responsive domain size and disrupted maturation of glutamate uptake following neonatal cortical freeze-lesion
por: Armbruster, Moritz, et al.
Publicado: (2014)

The dual role of chloride in synaptic vesicle glutamate transport
por: Chang, Roger, et al.
Publicado: (2018)

Extracellular Glutamate: Functional Compartments Operate in Different Concentration Ranges
por: Moussawi, Khaled, et al.
Publicado: (2011)

Plasticity of Astrocytic Coverage and Glutamate Transporter Expression in Adult Mouse Cortex
por: Genoud, Christel, et al.
Publicado: (2006)

Glutamate Uptake Triggers Transporter-Mediated GABA Release from Astrocytes
por: Héja, László, et al.
Publicado: (2009)

Lesion-Induced Alterations in Astrocyte Glutamate Transporter Expression and Function in the Hippocampus
por: Schreiner, Alexandra E., et al.
Publicado: (2013)

Potassium and glutamate transport is impaired in scar-forming tumor-associated astrocytes
por: Campbell, Susan C., et al.
Publicado: (2019)

Enhancement of Phosphorylation and Transport Activity of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter 3 by C3bot and a 26mer C3bot Peptide
por: Piepgras, Johannes, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2kde03dpdck6dtii8r0noam15s