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iTRAQ-Based Proteomic Analysis of Polyploid Giant Cancer Cells and Budding Progeny Cells Reveals Several Distinct Pathways for Ovarian Cancer Development

Polyploid giant cancer cells (PGCCs) are a morphologically distinct subgroup of human tumor cells with increased nuclear size or multiple nuclei, but they are generally considered unimportant because they are presumed to be nondividing and thus nonviable. We have recently shown that these large canc...

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Detalles Bibliográficos
Autores principales: Zhang, Shiwu, Mercado-Uribe, Imelda, Hanash, Samir, Liu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858113/
https://www.ncbi.nlm.nih.gov/pubmed/24348907
http://dx.doi.org/10.1371/journal.pone.0080120