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Antimicrobial surfaces for craniofacial implants: state of the art

In an attempt to regain function and aesthetics in the craniofacial region, different biomaterials, including titanium, hydroxyapatite, biodegradable polymers and composites, have been widely used as a result of the loss of craniofacial bone. Although these materials presented favorable success rate...

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Autores principales: Actis, Lisa, Gaviria, Laura, Guda, Teja, Ong, Joo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Oral and Maxillofacial Surgeons 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858148/
https://www.ncbi.nlm.nih.gov/pubmed/24471018
http://dx.doi.org/10.5125/jkaoms.2013.39.2.43
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author Actis, Lisa
Gaviria, Laura
Guda, Teja
Ong, Joo L.
author_facet Actis, Lisa
Gaviria, Laura
Guda, Teja
Ong, Joo L.
author_sort Actis, Lisa
collection PubMed
description In an attempt to regain function and aesthetics in the craniofacial region, different biomaterials, including titanium, hydroxyapatite, biodegradable polymers and composites, have been widely used as a result of the loss of craniofacial bone. Although these materials presented favorable success rates, osseointegration and antibacterial properties are often hard to achieve. Although bone-implant interactions are highly dependent on the implant's surface characteristics, infections following traumatic craniofacial injuries are common. As such, poor osseointegration and infections are two of the many causes of implant failure. Further, as increasingly complex dental repairs are attempted, the likelihood of infection in these implants has also been on the rise. For these reasons, the treatment of craniofacial bone defects and dental repairs for long-term success remains a challenge. Various approaches to reduce the rate of infection and improve osseointegration have been investigated. Furthermore, recent and planned tissue engineering developments are aimed at improving the implants' physical and biological properties by improving their surfaces in order to develop craniofacial bone substitutes that will restore, maintain and improve tissue function. In this review, the commonly used biomaterials for craniofacial bone restoration and dental repair, as well as surface modification techniques, antibacterial surfaces and coatings are discussed.
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spelling pubmed-38581482014-01-27 Antimicrobial surfaces for craniofacial implants: state of the art Actis, Lisa Gaviria, Laura Guda, Teja Ong, Joo L. J Korean Assoc Oral Maxillofac Surg Review Article In an attempt to regain function and aesthetics in the craniofacial region, different biomaterials, including titanium, hydroxyapatite, biodegradable polymers and composites, have been widely used as a result of the loss of craniofacial bone. Although these materials presented favorable success rates, osseointegration and antibacterial properties are often hard to achieve. Although bone-implant interactions are highly dependent on the implant's surface characteristics, infections following traumatic craniofacial injuries are common. As such, poor osseointegration and infections are two of the many causes of implant failure. Further, as increasingly complex dental repairs are attempted, the likelihood of infection in these implants has also been on the rise. For these reasons, the treatment of craniofacial bone defects and dental repairs for long-term success remains a challenge. Various approaches to reduce the rate of infection and improve osseointegration have been investigated. Furthermore, recent and planned tissue engineering developments are aimed at improving the implants' physical and biological properties by improving their surfaces in order to develop craniofacial bone substitutes that will restore, maintain and improve tissue function. In this review, the commonly used biomaterials for craniofacial bone restoration and dental repair, as well as surface modification techniques, antibacterial surfaces and coatings are discussed. The Korean Association of Oral and Maxillofacial Surgeons 2013-04 2013-04-23 /pmc/articles/PMC3858148/ /pubmed/24471018 http://dx.doi.org/10.5125/jkaoms.2013.39.2.43 Text en Copyright © 2013 The Korean Association of Oral and Maxillofacial Surgeons. All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Actis, Lisa
Gaviria, Laura
Guda, Teja
Ong, Joo L.
Antimicrobial surfaces for craniofacial implants: state of the art
title Antimicrobial surfaces for craniofacial implants: state of the art
title_full Antimicrobial surfaces for craniofacial implants: state of the art
title_fullStr Antimicrobial surfaces for craniofacial implants: state of the art
title_full_unstemmed Antimicrobial surfaces for craniofacial implants: state of the art
title_short Antimicrobial surfaces for craniofacial implants: state of the art
title_sort antimicrobial surfaces for craniofacial implants: state of the art
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858148/
https://www.ncbi.nlm.nih.gov/pubmed/24471018
http://dx.doi.org/10.5125/jkaoms.2013.39.2.43
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