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Antimicrobial surfaces for craniofacial implants: state of the art
In an attempt to regain function and aesthetics in the craniofacial region, different biomaterials, including titanium, hydroxyapatite, biodegradable polymers and composites, have been widely used as a result of the loss of craniofacial bone. Although these materials presented favorable success rate...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Oral and Maxillofacial Surgeons
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858148/ https://www.ncbi.nlm.nih.gov/pubmed/24471018 http://dx.doi.org/10.5125/jkaoms.2013.39.2.43 |
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author | Actis, Lisa Gaviria, Laura Guda, Teja Ong, Joo L. |
author_facet | Actis, Lisa Gaviria, Laura Guda, Teja Ong, Joo L. |
author_sort | Actis, Lisa |
collection | PubMed |
description | In an attempt to regain function and aesthetics in the craniofacial region, different biomaterials, including titanium, hydroxyapatite, biodegradable polymers and composites, have been widely used as a result of the loss of craniofacial bone. Although these materials presented favorable success rates, osseointegration and antibacterial properties are often hard to achieve. Although bone-implant interactions are highly dependent on the implant's surface characteristics, infections following traumatic craniofacial injuries are common. As such, poor osseointegration and infections are two of the many causes of implant failure. Further, as increasingly complex dental repairs are attempted, the likelihood of infection in these implants has also been on the rise. For these reasons, the treatment of craniofacial bone defects and dental repairs for long-term success remains a challenge. Various approaches to reduce the rate of infection and improve osseointegration have been investigated. Furthermore, recent and planned tissue engineering developments are aimed at improving the implants' physical and biological properties by improving their surfaces in order to develop craniofacial bone substitutes that will restore, maintain and improve tissue function. In this review, the commonly used biomaterials for craniofacial bone restoration and dental repair, as well as surface modification techniques, antibacterial surfaces and coatings are discussed. |
format | Online Article Text |
id | pubmed-3858148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | The Korean Association of Oral and Maxillofacial Surgeons |
record_format | MEDLINE/PubMed |
spelling | pubmed-38581482014-01-27 Antimicrobial surfaces for craniofacial implants: state of the art Actis, Lisa Gaviria, Laura Guda, Teja Ong, Joo L. J Korean Assoc Oral Maxillofac Surg Review Article In an attempt to regain function and aesthetics in the craniofacial region, different biomaterials, including titanium, hydroxyapatite, biodegradable polymers and composites, have been widely used as a result of the loss of craniofacial bone. Although these materials presented favorable success rates, osseointegration and antibacterial properties are often hard to achieve. Although bone-implant interactions are highly dependent on the implant's surface characteristics, infections following traumatic craniofacial injuries are common. As such, poor osseointegration and infections are two of the many causes of implant failure. Further, as increasingly complex dental repairs are attempted, the likelihood of infection in these implants has also been on the rise. For these reasons, the treatment of craniofacial bone defects and dental repairs for long-term success remains a challenge. Various approaches to reduce the rate of infection and improve osseointegration have been investigated. Furthermore, recent and planned tissue engineering developments are aimed at improving the implants' physical and biological properties by improving their surfaces in order to develop craniofacial bone substitutes that will restore, maintain and improve tissue function. In this review, the commonly used biomaterials for craniofacial bone restoration and dental repair, as well as surface modification techniques, antibacterial surfaces and coatings are discussed. The Korean Association of Oral and Maxillofacial Surgeons 2013-04 2013-04-23 /pmc/articles/PMC3858148/ /pubmed/24471018 http://dx.doi.org/10.5125/jkaoms.2013.39.2.43 Text en Copyright © 2013 The Korean Association of Oral and Maxillofacial Surgeons. All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Actis, Lisa Gaviria, Laura Guda, Teja Ong, Joo L. Antimicrobial surfaces for craniofacial implants: state of the art |
title | Antimicrobial surfaces for craniofacial implants: state of the art |
title_full | Antimicrobial surfaces for craniofacial implants: state of the art |
title_fullStr | Antimicrobial surfaces for craniofacial implants: state of the art |
title_full_unstemmed | Antimicrobial surfaces for craniofacial implants: state of the art |
title_short | Antimicrobial surfaces for craniofacial implants: state of the art |
title_sort | antimicrobial surfaces for craniofacial implants: state of the art |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858148/ https://www.ncbi.nlm.nih.gov/pubmed/24471018 http://dx.doi.org/10.5125/jkaoms.2013.39.2.43 |
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