Cargando…

Decreased Galectin-9 and Increased Tim-3 Expression Are Related to Poor Prognosis in Gastric Cancer

INTRODUCTION: Galectin-9 (Gal-9) induces adhesion and aggregation of certain cell types and inhibits the metastasis of tumor cells. T-cell immunoglobulin–and mucin domain-3–containing molecule 3 (TIM-3) plays a pivotal role in immune regulation. The aim of this study is to investigate Gal-9 and TIM-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Jing, Jin, Mei-Shan, Kong, Fei, Cao, Donghui, Ma, Hong-Xi, Jia, Zhifang, Wang, Yin-Ping, Suo, Jian, Cao, Xueyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858245/ https://www.ncbi.nlm.nih.gov/pubmed/24339967 http://dx.doi.org/10.1371/journal.pone.0081799

Ejemplares similares

Galectin-3 not Galectin-9 as a candidate prognosis marker for hepatocellular carcinoma
por: Kong, Fei, et al.
Publicado: (2020)

CD44 but not CD24 expression is related to poor prognosis in non-cardia adenocarcinoma of the stomach
por: Cao, Xueyuan, et al.
Publicado: (2014)

Polymorphisms of the DNA Methyltransferase 1 Associated with Reduced Risks of Helicobacter pylori Infection and Increased Risks of Gastric Atrophy
por: Jiang, Jing, et al.
Publicado: (2012)

Tim3 binding to galectin-9 stimulates antimicrobial immunity
por: Jayaraman, Pushpa, et al.
Publicado: (2010)

TIM-3 Does Not Act as a Receptor for Galectin-9
por: Leitner, Judith, et al.
Publicado: (2013)

PD-1 and PD-L1 co-expression predicts favorable prognosis in gastric cancer
por: Wu, Yanhua, et al.
Publicado: (2017)

Polymorphism of DNA Methyltransferase 3b and Association with Development and Prognosis in Gastric Cancer
por: Wang, Chuan, et al.
Publicado: (2015)

The Variations’ in Genes Encoding TIM-3 and Its Ligand, Galectin-9, Influence on ccRCC Risk and Prognosis
por: Andrzejczak, Anna, et al.
Publicado: (2023)

Galectin-9 expression predicts poor prognosis in hepatitis B virus-associated hepatocellular carcinoma
por: Jiao, Jianhua, et al.
Publicado: (2022)

Long non-coding RNA polymorphisms on 8q24 are associated with the prognosis of gastric cancer in a Chinese population
por: Zhang, Yangyu, et al.
Publicado: (2020)

Positive H. pylori status predicts better prognosis of non-cardiac gastric cancer patients: results from cohort study and meta-analysis
por: Jia, Zhifang, et al.
Publicado: (2022)

The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer
por: Yasinska, Inna M., et al.
Publicado: (2019)

Association of polymorphism of PTPN 11 encoding SHP-2 with gastric atrophy but not gastric cancer in Helicobacter pylori seropositive Chinese population
por: Jiang, Jing, et al.
Publicado: (2012)

Canolol Inhibits Gastric Tumors Initiation and Progression through COX-2/PGE2 Pathway in K19-C2mE Transgenic Mice
por: Cao, Donghui, et al.
Publicado: (2015)

The Protective Effects of 18β-Glycyrrhetinic Acid on Helicobacter pylori-Infected Gastric Mucosa in Mongolian Gerbils
por: Cao, Donghui, et al.
Publicado: (2016)

Involvement of Galectin-9/TIM-3 Pathway in the Systemic Inflammatory Response in Early-Onset Preeclampsia
por: Miko, Eva, et al.
Publicado: (2013)

The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells
por: Gonçalves Silva, Isabel, et al.
Publicado: (2016)

Galectin-1-mediated high NCAPG expression correlates with poor prognosis in gastric cancer
por: Zheng, Tingrui, et al.
Publicado: (2023)

Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy
por: Yang, Riyao, et al.
Publicado: (2021)

Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis
por: Wu, Yanhua, et al.
Publicado: (2017)

Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection
por: Nebbia, Gaia, et al.
Publicado: (2012)

Functional expression of Tim-3 on blasts and clinical impact of its ligand galectin-9 in myelodysplastic syndromes
por: Asayama, Toshio, et al.
Publicado: (2017)

Upregulated Tim-3/galectin-9 expressions in acute lung injury in a murine malarial model
por: Liu, Jinfeng, et al.
Publicado: (2015)

Upregulation of Tim‐3 is associated with poor prognosis in acute myeloid leukemia
por: Wu, Zhengwei, et al.
Publicado: (2022)

Microsatellite instability and Epstein-Barr virus combined with PD-L1 could serve as a potential strategy for predicting the prognosis and efficacy of postoperative chemotherapy in gastric cancer
por: Yang, Na, et al.
Publicado: (2021)

Galectin-3 is associated with a poor prognosis in primary hepatocellular carcinoma
por: Jiang, Shan-Shan, et al.
Publicado: (2014)

18β-glycyrrhetinic acid suppresses gastric cancer by activation of miR-149-3p-Wnt-1 signaling
por: Cao, Donghui, et al.
Publicado: (2016)

Bone marrow‐derived mesenchymal stem cells inhibit NK cell function via Tim‐3/galectin‐9 in multiple myeloma patients
por: Liu, Zhao‐Yun, et al.
Publicado: (2023)

Poor Prognosis of Gastric Adenocarcinoma with Decreased Expression of AHRR
por: Li, Yuan-fang, et al.
Publicado: (2012)

Galectin-9/TIM-3 Interaction Regulates Virus-Specific Primary and Memory CD8(+) T Cell Response
por: Sehrawat, Sharvan, et al.
Publicado: (2010)

The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells
por: Gonçalves Silva, Isabel, et al.
Publicado: (2017)

Circulating T Cells Exhibit Different TIM3/Galectin-9 Expression in Patients with Obesity and Obesity-Related Diabetes
por: Sun, Lili, et al.
Publicado: (2020)

Different Expression Pattern of TIM-3 and Galectin-9 Molecules by Peripheral and Peritoneal Lymphocytes in Women with and without Endometriosis
por: Meggyes, Matyas, et al.
Publicado: (2020)

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson’s disease
por: Peng, Qinyu, et al.
Publicado: (2022)

Peripheral Blood TIM-3 Positive NK and CD8+ T Cells throughout Pregnancy: TIM-3/Galectin-9 Interaction and Its Possible Role during Pregnancy
por: Meggyes, Matyas, et al.
Publicado: (2014)

Tim-3 Is Upregulated in NK Cells during Early Pregnancy and Inhibits NK Cytotoxicity toward Trophoblast in Galectin-9 Dependent Pathway
por: Sun, Jintang, et al.
Publicado: (2016)

Molecular and immune correlates of TIM-3 (HAVCR2) and galectin 9 (LGALS9) mRNA expression and DNA methylation in melanoma
por: Holderried, Tobias A. W., et al.
Publicado: (2019)

Polymorphisms of the DNA Methyltransferase 1 Gene Predict Survival of Gastric Cancer Patients Receiving Tumorectomy
por: Jia, Zhifang, et al.
Publicado: (2016)

Decreased Expression of AZGP1 Is Associated with Poor Prognosis in Primary Gastric Cancer
por: Huang, Chun-yu, et al.
Publicado: (2013)

Tim-3-mediated signaling in NK cells may be modulated by increased Galectin-9 expression in HIV-1 infection
por: Jost, S, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_0gelom9qpfur0aosfp5ou94u1i