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Improving Embryonic Stem Cell Expansion through the Combination of Perfusion and Bioprocess Model Design
BACKGROUND: High proliferative and differentiation capacity renders embryonic stem cells (ESCs) a promising cell source for tissue engineering and cell-based therapies. Harnessing their potential, however, requires well-designed, efficient and reproducible expansion and differentiation protocols as...
Autores principales: | Yeo, David, Kiparissides, Alexandros, Cha, Jae Min, Aguilar-Gallardo, Cristobal, Polak, Julia M., Tsiridis, Elefterios, Pistikopoulos, Efstratios N., Mantalaris, Athanasios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858261/ https://www.ncbi.nlm.nih.gov/pubmed/24339957 http://dx.doi.org/10.1371/journal.pone.0081728 |
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