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Vitamin A Is a Negative Regulator of Osteoblast Mineralization

An excessive intake of vitamin A has been associated with an increased risk of fractures in humans. In animals, a high vitamin A intake leads to a reduction of long bone diameter and spontaneous fractures. Studies in rodents indicate that the bone thinning is due to increased periosteal bone resorpt...

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Detalles Bibliográficos
Autores principales: Lind, Thomas, Sundqvist, Anders, Hu, Lijuan, Pejler, Gunnar, Andersson, Göran, Jacobson, Annica, Melhus, Håkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858291/
https://www.ncbi.nlm.nih.gov/pubmed/24340023
http://dx.doi.org/10.1371/journal.pone.0082388