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Bone Marrow Stromal Cells Derived MCP-1 Reverses the Inhibitory Effects of Multiple Myeloma Cells on Osteoclastogenesis by Upregulating the RANK Expression

Multiple myeloma (MM) cells are responsible for aberrant osteoclast (OC) activation. However, when cocultured monocytes, but not OC precursors, with MM cells, we made a novel observation that MM cells inhibited receptor activator of nuclear factor κB ligand (RANKL)-induced increase of OC differentia...

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Detalles Bibliográficos
Autores principales:	Liu, Zhiqiang, Xu, Jingda, Li, Haiyan, Zheng, Yuhuan, He, Jin, Liu, Huan, Zhong, Yuping, Lu, Yong, Hong, Bangxing, Zhang, Mingjun, Lin, Pei, Du, Juan, Hou, Jian, Qian, Jianfei, Kwak, Larry W., Yi, Qing, Yang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858321/ https://www.ncbi.nlm.nih.gov/pubmed/24340030 http://dx.doi.org/10.1371/journal.pone.0082453

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