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Elevated Levels of Interferon-γ Production by Memory T Cells Do Not Promote Transplant Tolerance Resistance in Aged Recipients

Immunosenescence predisposes the elderly to infectious and autoimmune diseases and impairs the response to vaccination. We recently demonstrated that ageing also impedes development of transplantation tolerance. Unlike their young counterparts (8-12 weeks of age) aged male recipients (greater than 1...

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Detalles Bibliográficos
Autores principales:	Kim, James I., Stott, Ryan T., Soohoo, Julie, Lee, Kang Mi, Zhao, Gaoping, Yeh, Heidi, Deng, Shaoping, Markmann, James F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858330/ https://www.ncbi.nlm.nih.gov/pubmed/24340063 http://dx.doi.org/10.1371/journal.pone.0082856

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