Polymorphic Cytochrome P450 Enzymes (CYPs) and Their Role in Personalized Therapy

The cytochrome P450 (CYP) enzymes are major players in drug metabolism. More than 2,000 mutations have been described, and certain single nucleotide polymorphisms (SNPs) have been shown to have a large impact on CYP activity. Therefore, CYPs play an important role in inter-individual drug response a...

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Detalles Bibliográficos
Autores principales: Preissner, Sarah C., Hoffmann, Michael F., Preissner, Robert, Dunkel, Mathias, Gewiess, Andreas, Preissner, Saskia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858335/
https://www.ncbi.nlm.nih.gov/pubmed/24340040
http://dx.doi.org/10.1371/journal.pone.0082562

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