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Centrosomal Localisation of the Cancer/Testis (CT) Antigens NY-ESO-1 and MAGE-C1 Is Regulated by Proteasome Activity in Tumour Cells
The Cancer/Testis (CT) antigen family of genes are transcriptionally repressed in most human tissues but are atypically re-expressed in many malignant tumour types. Their restricted expression profile makes CT antigens ideal targets for cancer immunotherapy. As little is known about whether CT antig...
Autores principales: | Pagotto, Anna, Caballero, Otavia L., Volkmar, Norbert, Devalle, Sylvie, Simpson, Andrew J. G., Lu, Xin, Christianson, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858345/ https://www.ncbi.nlm.nih.gov/pubmed/24340093 http://dx.doi.org/10.1371/journal.pone.0083212 |
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