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Human pentatricopeptide proteins: Only a few and what do they do?
Pentatricopeptide repeat (PPR) proteins constitute a large family of RNA-binding proteins that contain a canonical 35 residue repeat motif. Originally identified in Arabidopsis thaliana, family members are found in protists, fungi, and metazoan but are by far most abundant in plant organelles. Seven...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858426/ https://www.ncbi.nlm.nih.gov/pubmed/23635806 http://dx.doi.org/10.4161/rna.24770 |
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author | Lightowlers, Robert N Chrzanowska-Lightowlers, Zofia MA |
author_facet | Lightowlers, Robert N Chrzanowska-Lightowlers, Zofia MA |
author_sort | Lightowlers, Robert N |
collection | PubMed |
description | Pentatricopeptide repeat (PPR) proteins constitute a large family of RNA-binding proteins that contain a canonical 35 residue repeat motif. Originally identified in Arabidopsis thaliana, family members are found in protists, fungi, and metazoan but are by far most abundant in plant organelles. Seven examples have been identified in human mitochondria and roles have been tentatively ascribed to each. In this review, we briefly outline each of these PPR proteins and discuss the role each is believed to play in facilitating mitochondrial gene expression. |
format | Online Article Text |
id | pubmed-3858426 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Landes Bioscience |
record_format | MEDLINE/PubMed |
spelling | pubmed-38584262013-12-16 Human pentatricopeptide proteins: Only a few and what do they do? Lightowlers, Robert N Chrzanowska-Lightowlers, Zofia MA RNA Biol Review Pentatricopeptide repeat (PPR) proteins constitute a large family of RNA-binding proteins that contain a canonical 35 residue repeat motif. Originally identified in Arabidopsis thaliana, family members are found in protists, fungi, and metazoan but are by far most abundant in plant organelles. Seven examples have been identified in human mitochondria and roles have been tentatively ascribed to each. In this review, we briefly outline each of these PPR proteins and discuss the role each is believed to play in facilitating mitochondrial gene expression. Landes Bioscience 2013-09-01 2013-04-23 /pmc/articles/PMC3858426/ /pubmed/23635806 http://dx.doi.org/10.4161/rna.24770 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Review Lightowlers, Robert N Chrzanowska-Lightowlers, Zofia MA Human pentatricopeptide proteins: Only a few and what do they do? |
title | Human pentatricopeptide proteins: Only a few and what do they do? |
title_full | Human pentatricopeptide proteins: Only a few and what do they do? |
title_fullStr | Human pentatricopeptide proteins: Only a few and what do they do? |
title_full_unstemmed | Human pentatricopeptide proteins: Only a few and what do they do? |
title_short | Human pentatricopeptide proteins: Only a few and what do they do? |
title_sort | human pentatricopeptide proteins: only a few and what do they do? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858426/ https://www.ncbi.nlm.nih.gov/pubmed/23635806 http://dx.doi.org/10.4161/rna.24770 |
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