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Human pentatricopeptide proteins: Only a few and what do they do?

Pentatricopeptide repeat (PPR) proteins constitute a large family of RNA-binding proteins that contain a canonical 35 residue repeat motif. Originally identified in Arabidopsis thaliana, family members are found in protists, fungi, and metazoan but are by far most abundant in plant organelles. Seven...

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Autores principales: Lightowlers, Robert N, Chrzanowska-Lightowlers, Zofia MA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858426/
https://www.ncbi.nlm.nih.gov/pubmed/23635806
http://dx.doi.org/10.4161/rna.24770
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author Lightowlers, Robert N
Chrzanowska-Lightowlers, Zofia MA
author_facet Lightowlers, Robert N
Chrzanowska-Lightowlers, Zofia MA
author_sort Lightowlers, Robert N
collection PubMed
description Pentatricopeptide repeat (PPR) proteins constitute a large family of RNA-binding proteins that contain a canonical 35 residue repeat motif. Originally identified in Arabidopsis thaliana, family members are found in protists, fungi, and metazoan but are by far most abundant in plant organelles. Seven examples have been identified in human mitochondria and roles have been tentatively ascribed to each. In this review, we briefly outline each of these PPR proteins and discuss the role each is believed to play in facilitating mitochondrial gene expression.
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spelling pubmed-38584262013-12-16 Human pentatricopeptide proteins: Only a few and what do they do? Lightowlers, Robert N Chrzanowska-Lightowlers, Zofia MA RNA Biol Review Pentatricopeptide repeat (PPR) proteins constitute a large family of RNA-binding proteins that contain a canonical 35 residue repeat motif. Originally identified in Arabidopsis thaliana, family members are found in protists, fungi, and metazoan but are by far most abundant in plant organelles. Seven examples have been identified in human mitochondria and roles have been tentatively ascribed to each. In this review, we briefly outline each of these PPR proteins and discuss the role each is believed to play in facilitating mitochondrial gene expression. Landes Bioscience 2013-09-01 2013-04-23 /pmc/articles/PMC3858426/ /pubmed/23635806 http://dx.doi.org/10.4161/rna.24770 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Review
Lightowlers, Robert N
Chrzanowska-Lightowlers, Zofia MA
Human pentatricopeptide proteins: Only a few and what do they do?
title Human pentatricopeptide proteins: Only a few and what do they do?
title_full Human pentatricopeptide proteins: Only a few and what do they do?
title_fullStr Human pentatricopeptide proteins: Only a few and what do they do?
title_full_unstemmed Human pentatricopeptide proteins: Only a few and what do they do?
title_short Human pentatricopeptide proteins: Only a few and what do they do?
title_sort human pentatricopeptide proteins: only a few and what do they do?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858426/
https://www.ncbi.nlm.nih.gov/pubmed/23635806
http://dx.doi.org/10.4161/rna.24770
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