The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth

Even with successful surgical resection and perioperative chemotherapy and radiation, pancreatic ductal adenocarcinoma (PDA) has a high incidence of recurrence. Tumor cell survival depends on activation of signaling pathways that suppress the apoptotic stimuli of invasion and metastasis. Focal adhes...

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Detalles Bibliográficos
Autores principales: Kurenova, Elena, Liao, Jianqun, He, Di-Hua, Hunt, Darrell, Yemma, Michael, Bshara, Wiam, Seshadri, Mukund, Cance, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858551/
https://www.ncbi.nlm.nih.gov/pubmed/24142503

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