Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer

Histone variants seem to play a major role in gene expression regulation. In prostate cancer, H2A.Z and its acetylated form are implicated in oncogenes' upregulation. SIRT1, which may act either as tumor suppressor or oncogene, reduces H2A.Z levels in cardiomyocytes, via proteasome-mediated deg...

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Detalles Bibliográficos
Autores principales: Baptista, Tiago, Graça, Inês, Sousa, Elsa J., Oliveira, Ana I., Costa, Natália R., Costa-Pinheiro, Pedro, Amado, Francisco, Henrique, Rui, Jerónimo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858554/
https://www.ncbi.nlm.nih.gov/pubmed/24127549

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