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Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine
The embryonic T-box transcription factor brachyury is aberrantly expressed in a range of human tumors. Previous studies have demonstrated that brachyury is a driver of the epithelial-mesenchymal transition (EMT), a process associated with cancer progression. Brachyury expression in human tumor cells...
Autores principales: | Hamilton, Duane H., Litzinger, Mary T., Jales, Alessandra, Huang, Bruce, Fernando, Romaine I., Hodge, James W., Ardiani, Andressa, Apelian, David, Schlom, Jeffrey, Palena, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858563/ https://www.ncbi.nlm.nih.gov/pubmed/24125763 |
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