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Late onset of atypical paroxysmal non-kinesigenic dyskinesia with remote history of Graves’ disease

Paroxysmal non-kinesigenic dyskinesia (PNKD) is a rare hyperkinetic movement disorder and falls under the category of paroxysmal movement disorders. In this condition, episodes are spontaneous, involuntary, and involve dystonic posturing with choreic and ballistic movements. Attacks last for minutes...

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Autores principales: Rana, Abdul Qayyum, Nadeem, Ambreen, Yousuf, Muhammad Saad, Kachhvi, Zakerabibi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858768/
https://www.ncbi.nlm.nih.gov/pubmed/24347956
http://dx.doi.org/10.4103/0976-3147.120226
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author Rana, Abdul Qayyum
Nadeem, Ambreen
Yousuf, Muhammad Saad
Kachhvi, Zakerabibi M.
author_facet Rana, Abdul Qayyum
Nadeem, Ambreen
Yousuf, Muhammad Saad
Kachhvi, Zakerabibi M.
author_sort Rana, Abdul Qayyum
collection PubMed
description Paroxysmal non-kinesigenic dyskinesia (PNKD) is a rare hyperkinetic movement disorder and falls under the category of paroxysmal movement disorders. In this condition, episodes are spontaneous, involuntary, and involve dystonic posturing with choreic and ballistic movements. Attacks last for minutes to hours and rarely occur more than once per day. Attacks are not typically triggered by sudden movement, but may be brought on by alcohol, caffeine, stress, fatigue, or chocolate. We report a patient with multiple atypical features of PNKD. She had a 7-year history of this condition with onset at the age of 59, and a remote history of Graves’ disease requiring total thyroidectomy. The frequency of attacks in our case ranged from five to six times a day to a minimum of twice per week, and the duration of episode was short, lasting not more than 2 min. Typically, PNKDs occur at a much younger age and have longer attack durations with low frequency. Administering clonazepam worked to reduce her symptoms, although majority of previous research suggests that pharmacological interventions have poor outcomes.
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spelling pubmed-38587682013-12-16 Late onset of atypical paroxysmal non-kinesigenic dyskinesia with remote history of Graves’ disease Rana, Abdul Qayyum Nadeem, Ambreen Yousuf, Muhammad Saad Kachhvi, Zakerabibi M. J Neurosci Rural Pract Case Report Paroxysmal non-kinesigenic dyskinesia (PNKD) is a rare hyperkinetic movement disorder and falls under the category of paroxysmal movement disorders. In this condition, episodes are spontaneous, involuntary, and involve dystonic posturing with choreic and ballistic movements. Attacks last for minutes to hours and rarely occur more than once per day. Attacks are not typically triggered by sudden movement, but may be brought on by alcohol, caffeine, stress, fatigue, or chocolate. We report a patient with multiple atypical features of PNKD. She had a 7-year history of this condition with onset at the age of 59, and a remote history of Graves’ disease requiring total thyroidectomy. The frequency of attacks in our case ranged from five to six times a day to a minimum of twice per week, and the duration of episode was short, lasting not more than 2 min. Typically, PNKDs occur at a much younger age and have longer attack durations with low frequency. Administering clonazepam worked to reduce her symptoms, although majority of previous research suggests that pharmacological interventions have poor outcomes. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3858768/ /pubmed/24347956 http://dx.doi.org/10.4103/0976-3147.120226 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Rana, Abdul Qayyum
Nadeem, Ambreen
Yousuf, Muhammad Saad
Kachhvi, Zakerabibi M.
Late onset of atypical paroxysmal non-kinesigenic dyskinesia with remote history of Graves’ disease
title Late onset of atypical paroxysmal non-kinesigenic dyskinesia with remote history of Graves’ disease
title_full Late onset of atypical paroxysmal non-kinesigenic dyskinesia with remote history of Graves’ disease
title_fullStr Late onset of atypical paroxysmal non-kinesigenic dyskinesia with remote history of Graves’ disease
title_full_unstemmed Late onset of atypical paroxysmal non-kinesigenic dyskinesia with remote history of Graves’ disease
title_short Late onset of atypical paroxysmal non-kinesigenic dyskinesia with remote history of Graves’ disease
title_sort late onset of atypical paroxysmal non-kinesigenic dyskinesia with remote history of graves’ disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858768/
https://www.ncbi.nlm.nih.gov/pubmed/24347956
http://dx.doi.org/10.4103/0976-3147.120226
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