Cargando…

Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors

BACKGROUND: The glomus jugulare tumor is a slowly growing benign neoplasm originating from neural crest. There is a high morbidity associated with surgical resection of glomus jugulare. Radiosurgery play a relevant role as a therapeutic option in these tumors and its use has grown in popularity. The...

Descripción completa

Detalles Bibliográficos
Autores principales: de Andrade, Emerson Magno, Brito, José Reginaldo, Mario, Susana Dias, de Melo, Suely Maymone, Benabou, Salomon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858802/
https://www.ncbi.nlm.nih.gov/pubmed/24349866
http://dx.doi.org/10.4103/2152-7806.121629
_version_ 1782295332294492160
author de Andrade, Emerson Magno
Brito, José Reginaldo
Mario, Susana Dias
de Melo, Suely Maymone
Benabou, Salomon
author_facet de Andrade, Emerson Magno
Brito, José Reginaldo
Mario, Susana Dias
de Melo, Suely Maymone
Benabou, Salomon
author_sort de Andrade, Emerson Magno
collection PubMed
description BACKGROUND: The glomus jugulare tumor is a slowly growing benign neoplasm originating from neural crest. There is a high morbidity associated with surgical resection of glomus jugulare. Radiosurgery play a relevant role as a therapeutic option in these tumors and its use has grown in popularity. The authors describe a retrospective series of 15 patients and reviewed the literature about the glomus jugulare tumors. METHODS: We reviewed retrospectively the data of 15 patients treated with stereotactic linear accelerator stereotactic radiosurgery (LINAC) radiosurgery between 2006 and 2011. RESULTS: The average tumor volume was 18.5 cm(3). The radiation dose to the tumor margin ranged between 12 and 20 Gy. The neurological status improved in three patients and remained unchanged in 12 patients. One patient developed a transient 7(th) nerve palsy that improved after clinical treatment. All tumors remained stable in size on follow-up with resonance magnetic images. CONCLUSIONS: The radiosurgery is a safe and effective therapy for patients with glomus jugulare tumor. Despite the short follow-up period and the limited number of patients analyzed, we can infer that radiosurgery produce a tumor growth control with low morbidity, and may be used as a good option to surgical resection in selected cases.
format Online
Article
Text
id pubmed-3858802
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-38588022013-12-16 Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors de Andrade, Emerson Magno Brito, José Reginaldo Mario, Susana Dias de Melo, Suely Maymone Benabou, Salomon Surg Neurol Int Surgical Neurology International: Stereotactic BACKGROUND: The glomus jugulare tumor is a slowly growing benign neoplasm originating from neural crest. There is a high morbidity associated with surgical resection of glomus jugulare. Radiosurgery play a relevant role as a therapeutic option in these tumors and its use has grown in popularity. The authors describe a retrospective series of 15 patients and reviewed the literature about the glomus jugulare tumors. METHODS: We reviewed retrospectively the data of 15 patients treated with stereotactic linear accelerator stereotactic radiosurgery (LINAC) radiosurgery between 2006 and 2011. RESULTS: The average tumor volume was 18.5 cm(3). The radiation dose to the tumor margin ranged between 12 and 20 Gy. The neurological status improved in three patients and remained unchanged in 12 patients. One patient developed a transient 7(th) nerve palsy that improved after clinical treatment. All tumors remained stable in size on follow-up with resonance magnetic images. CONCLUSIONS: The radiosurgery is a safe and effective therapy for patients with glomus jugulare tumor. Despite the short follow-up period and the limited number of patients analyzed, we can infer that radiosurgery produce a tumor growth control with low morbidity, and may be used as a good option to surgical resection in selected cases. Medknow Publications & Media Pvt Ltd 2013-11-20 /pmc/articles/PMC3858802/ /pubmed/24349866 http://dx.doi.org/10.4103/2152-7806.121629 Text en Copyright: © 2013 de Andrade EM. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Surgical Neurology International: Stereotactic
de Andrade, Emerson Magno
Brito, José Reginaldo
Mario, Susana Dias
de Melo, Suely Maymone
Benabou, Salomon
Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors
title Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors
title_full Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors
title_fullStr Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors
title_full_unstemmed Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors
title_short Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors
title_sort stereotactic radiosurgery for the treatment of glomus jugulare tumors
topic Surgical Neurology International: Stereotactic
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858802/
https://www.ncbi.nlm.nih.gov/pubmed/24349866
http://dx.doi.org/10.4103/2152-7806.121629
work_keys_str_mv AT deandradeemersonmagno stereotacticradiosurgeryforthetreatmentofglomusjugularetumors
AT britojosereginaldo stereotacticradiosurgeryforthetreatmentofglomusjugularetumors
AT mariosusanadias stereotacticradiosurgeryforthetreatmentofglomusjugularetumors
AT demelosuelymaymone stereotacticradiosurgeryforthetreatmentofglomusjugularetumors
AT benabousalomon stereotacticradiosurgeryforthetreatmentofglomusjugularetumors