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Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors
BACKGROUND: The glomus jugulare tumor is a slowly growing benign neoplasm originating from neural crest. There is a high morbidity associated with surgical resection of glomus jugulare. Radiosurgery play a relevant role as a therapeutic option in these tumors and its use has grown in popularity. The...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858802/ https://www.ncbi.nlm.nih.gov/pubmed/24349866 http://dx.doi.org/10.4103/2152-7806.121629 |
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author | de Andrade, Emerson Magno Brito, José Reginaldo Mario, Susana Dias de Melo, Suely Maymone Benabou, Salomon |
author_facet | de Andrade, Emerson Magno Brito, José Reginaldo Mario, Susana Dias de Melo, Suely Maymone Benabou, Salomon |
author_sort | de Andrade, Emerson Magno |
collection | PubMed |
description | BACKGROUND: The glomus jugulare tumor is a slowly growing benign neoplasm originating from neural crest. There is a high morbidity associated with surgical resection of glomus jugulare. Radiosurgery play a relevant role as a therapeutic option in these tumors and its use has grown in popularity. The authors describe a retrospective series of 15 patients and reviewed the literature about the glomus jugulare tumors. METHODS: We reviewed retrospectively the data of 15 patients treated with stereotactic linear accelerator stereotactic radiosurgery (LINAC) radiosurgery between 2006 and 2011. RESULTS: The average tumor volume was 18.5 cm(3). The radiation dose to the tumor margin ranged between 12 and 20 Gy. The neurological status improved in three patients and remained unchanged in 12 patients. One patient developed a transient 7(th) nerve palsy that improved after clinical treatment. All tumors remained stable in size on follow-up with resonance magnetic images. CONCLUSIONS: The radiosurgery is a safe and effective therapy for patients with glomus jugulare tumor. Despite the short follow-up period and the limited number of patients analyzed, we can infer that radiosurgery produce a tumor growth control with low morbidity, and may be used as a good option to surgical resection in selected cases. |
format | Online Article Text |
id | pubmed-3858802 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38588022013-12-16 Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors de Andrade, Emerson Magno Brito, José Reginaldo Mario, Susana Dias de Melo, Suely Maymone Benabou, Salomon Surg Neurol Int Surgical Neurology International: Stereotactic BACKGROUND: The glomus jugulare tumor is a slowly growing benign neoplasm originating from neural crest. There is a high morbidity associated with surgical resection of glomus jugulare. Radiosurgery play a relevant role as a therapeutic option in these tumors and its use has grown in popularity. The authors describe a retrospective series of 15 patients and reviewed the literature about the glomus jugulare tumors. METHODS: We reviewed retrospectively the data of 15 patients treated with stereotactic linear accelerator stereotactic radiosurgery (LINAC) radiosurgery between 2006 and 2011. RESULTS: The average tumor volume was 18.5 cm(3). The radiation dose to the tumor margin ranged between 12 and 20 Gy. The neurological status improved in three patients and remained unchanged in 12 patients. One patient developed a transient 7(th) nerve palsy that improved after clinical treatment. All tumors remained stable in size on follow-up with resonance magnetic images. CONCLUSIONS: The radiosurgery is a safe and effective therapy for patients with glomus jugulare tumor. Despite the short follow-up period and the limited number of patients analyzed, we can infer that radiosurgery produce a tumor growth control with low morbidity, and may be used as a good option to surgical resection in selected cases. Medknow Publications & Media Pvt Ltd 2013-11-20 /pmc/articles/PMC3858802/ /pubmed/24349866 http://dx.doi.org/10.4103/2152-7806.121629 Text en Copyright: © 2013 de Andrade EM. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Surgical Neurology International: Stereotactic de Andrade, Emerson Magno Brito, José Reginaldo Mario, Susana Dias de Melo, Suely Maymone Benabou, Salomon Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors |
title | Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors |
title_full | Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors |
title_fullStr | Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors |
title_full_unstemmed | Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors |
title_short | Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors |
title_sort | stereotactic radiosurgery for the treatment of glomus jugulare tumors |
topic | Surgical Neurology International: Stereotactic |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858802/ https://www.ncbi.nlm.nih.gov/pubmed/24349866 http://dx.doi.org/10.4103/2152-7806.121629 |
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