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Cholinergic neurons—keeping check on amyloid β in the cerebral cortex
The physiological relevance of p75 neurotrophin receptor-mediated internalization of ligands with no apparent trophic functions by nerve cells remains unclear. Herein, we propose a homeostatic role for this in clearance of amyloid β (Aβ) in the brain. We hypothesize that uptake of Aβ in conjunction...
Autores principales: | Ovsepian, Saak V., Herms, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858826/ https://www.ncbi.nlm.nih.gov/pubmed/24376398 http://dx.doi.org/10.3389/fncel.2013.00252 |
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