The Protective Effect of Lidocaine on Septic Rats via the Inhibition of High Mobility Group Box 1 Expression and NF-κB Activation

Lidocaine, a common local anesthetic drug, has anti-inflammatory effects. It has demonstrated a protective effect in mice from septic peritonitis. However, it is unknown whether lidocaine has effects on high mobility group box 1 (HMGB1), a key mediator of inflammation. In this study, we investigated...

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Detalles Bibliográficos
Autores principales: Wang, Huan-Liang, Xing, Yan-Qiu, Xu, Ying-Xue, Rong, Fei, Lei, Wei-Fu, Zhang, Wen-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858876/
https://www.ncbi.nlm.nih.gov/pubmed/24371375
http://dx.doi.org/10.1155/2013/570370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858876/
https://www.ncbi.nlm.nih.gov/pubmed/24371375
http://dx.doi.org/10.1155/2013/570370

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