Cargando…

Fly model causes neurological rethink

A Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach.

Detalles Bibliográficos
Autores principales: Sadanandappa, Madhumala K, Ramaswami, Mani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859177/
https://www.ncbi.nlm.nih.gov/pubmed/24336781
http://dx.doi.org/10.7554/eLife.01820
_version_ 1782295389898014720
author Sadanandappa, Madhumala K
Ramaswami, Mani
author_facet Sadanandappa, Madhumala K
Ramaswami, Mani
author_sort Sadanandappa, Madhumala K
collection PubMed
description A Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach.
format Online
Article
Text
id pubmed-3859177
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher eLife Sciences Publications, Ltd
record_format MEDLINE/PubMed
spelling pubmed-38591772013-12-12 Fly model causes neurological rethink Sadanandappa, Madhumala K Ramaswami, Mani eLife Neuroscience A Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach. eLife Sciences Publications, Ltd 2013-12-11 /pmc/articles/PMC3859177/ /pubmed/24336781 http://dx.doi.org/10.7554/eLife.01820 Text en Copyright © 2013, Sadanandappa and Ramaswami http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
Sadanandappa, Madhumala K
Ramaswami, Mani
Fly model causes neurological rethink
title Fly model causes neurological rethink
title_full Fly model causes neurological rethink
title_fullStr Fly model causes neurological rethink
title_full_unstemmed Fly model causes neurological rethink
title_short Fly model causes neurological rethink
title_sort fly model causes neurological rethink
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859177/
https://www.ncbi.nlm.nih.gov/pubmed/24336781
http://dx.doi.org/10.7554/eLife.01820
work_keys_str_mv AT sadanandappamadhumalak flymodelcausesneurologicalrethink
AT ramaswamimani flymodelcausesneurologicalrethink