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Fly model causes neurological rethink
A Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859177/ https://www.ncbi.nlm.nih.gov/pubmed/24336781 http://dx.doi.org/10.7554/eLife.01820 |
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author | Sadanandappa, Madhumala K Ramaswami, Mani |
author_facet | Sadanandappa, Madhumala K Ramaswami, Mani |
author_sort | Sadanandappa, Madhumala K |
collection | PubMed |
description | A Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach. |
format | Online Article Text |
id | pubmed-3859177 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38591772013-12-12 Fly model causes neurological rethink Sadanandappa, Madhumala K Ramaswami, Mani eLife Neuroscience A Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach. eLife Sciences Publications, Ltd 2013-12-11 /pmc/articles/PMC3859177/ /pubmed/24336781 http://dx.doi.org/10.7554/eLife.01820 Text en Copyright © 2013, Sadanandappa and Ramaswami http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Neuroscience Sadanandappa, Madhumala K Ramaswami, Mani Fly model causes neurological rethink |
title | Fly model causes neurological rethink |
title_full | Fly model causes neurological rethink |
title_fullStr | Fly model causes neurological rethink |
title_full_unstemmed | Fly model causes neurological rethink |
title_short | Fly model causes neurological rethink |
title_sort | fly model causes neurological rethink |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859177/ https://www.ncbi.nlm.nih.gov/pubmed/24336781 http://dx.doi.org/10.7554/eLife.01820 |
work_keys_str_mv | AT sadanandappamadhumalak flymodelcausesneurologicalrethink AT ramaswamimani flymodelcausesneurologicalrethink |