Serum Interleukin-18 Levels Are Associated with Physical Activity in Japanese Men

OBJECTIVE: To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men. METHODS: A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 lev...

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Autores principales: Oda, Kanae, Miyatake, Nobuyuki, Sakano, Noriko, Saito, Takeshi, Miyachi, Motohiko, Tabata, Izumi, Numata, Takeyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859484/
https://www.ncbi.nlm.nih.gov/pubmed/24349077
http://dx.doi.org/10.1371/journal.pone.0081497
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author Oda, Kanae
Miyatake, Nobuyuki
Sakano, Noriko
Saito, Takeshi
Miyachi, Motohiko
Tabata, Izumi
Numata, Takeyuki
author_facet Oda, Kanae
Miyatake, Nobuyuki
Sakano, Noriko
Saito, Takeshi
Miyachi, Motohiko
Tabata, Izumi
Numata, Takeyuki
author_sort Oda, Kanae
collection PubMed
description OBJECTIVE: To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men. METHODS: A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 levels, physical activity by uniaxial accelerometers, peak oxygen uptake and metabolic risk parameters were also evaluated. RESULTS: Serum IL-18 levels were 179.4±84.7 pg/mL. Physical activity evaluated by Σ[metabolic equivalents × h per week (METs⋅h/w)]was significantly and negatively correlated with serum IL-18 levels (r = −0.252, p = 0.0235). These associations remained even after adjusting for age, peak oxygen uptake and other confounding factors. CONCLUSION: Serum IL-18 levels were closely associated with physical activity independent of peak oxygen uptake in Japanese men.
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spelling pubmed-38594842013-12-13 Serum Interleukin-18 Levels Are Associated with Physical Activity in Japanese Men Oda, Kanae Miyatake, Nobuyuki Sakano, Noriko Saito, Takeshi Miyachi, Motohiko Tabata, Izumi Numata, Takeyuki PLoS One Research Article OBJECTIVE: To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men. METHODS: A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 levels, physical activity by uniaxial accelerometers, peak oxygen uptake and metabolic risk parameters were also evaluated. RESULTS: Serum IL-18 levels were 179.4±84.7 pg/mL. Physical activity evaluated by Σ[metabolic equivalents × h per week (METs⋅h/w)]was significantly and negatively correlated with serum IL-18 levels (r = −0.252, p = 0.0235). These associations remained even after adjusting for age, peak oxygen uptake and other confounding factors. CONCLUSION: Serum IL-18 levels were closely associated with physical activity independent of peak oxygen uptake in Japanese men. Public Library of Science 2013-12-11 /pmc/articles/PMC3859484/ /pubmed/24349077 http://dx.doi.org/10.1371/journal.pone.0081497 Text en © 2013 Oda et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Oda, Kanae
Miyatake, Nobuyuki
Sakano, Noriko
Saito, Takeshi
Miyachi, Motohiko
Tabata, Izumi
Numata, Takeyuki
Serum Interleukin-18 Levels Are Associated with Physical Activity in Japanese Men
title Serum Interleukin-18 Levels Are Associated with Physical Activity in Japanese Men
title_full Serum Interleukin-18 Levels Are Associated with Physical Activity in Japanese Men
title_fullStr Serum Interleukin-18 Levels Are Associated with Physical Activity in Japanese Men
title_full_unstemmed Serum Interleukin-18 Levels Are Associated with Physical Activity in Japanese Men
title_short Serum Interleukin-18 Levels Are Associated with Physical Activity in Japanese Men
title_sort serum interleukin-18 levels are associated with physical activity in japanese men
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859484/
https://www.ncbi.nlm.nih.gov/pubmed/24349077
http://dx.doi.org/10.1371/journal.pone.0081497
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