Transglutaminase 2 Contributes to Apoptosis Induction in Jurkat T Cells by Modulating Ca(2+) Homeostasis via Cross-Linking RAP1GDS1

BACKGROUND: Transglutaminase 2 (TG2) is a protein cross-linking enzyme known to be associated with the in vivo apoptosis program of T cells. However, its role in the T cell apoptosis program was not investigated yet. RESULTS: Here we report that timed overexpression of both the wild type (wt) and th...

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Detalles Bibliográficos
Autores principales: Hsieh, Yu-Fan, Liu, Guang-Yaw, Lee, Yi-Ju, Yang, Jiann-Jou, Sándor, Katalin, Sarang, Zsolt, Bononi, Angela, Pinton, Paolo, Tretter, László, Szondy, Zsuzsa, Tsay, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859493/
https://www.ncbi.nlm.nih.gov/pubmed/24349085
http://dx.doi.org/10.1371/journal.pone.0081516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859493/
https://www.ncbi.nlm.nih.gov/pubmed/24349085
http://dx.doi.org/10.1371/journal.pone.0081516

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