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Insulin Protects Apoptotic Cardiomyocytes from Hypoxia/Reoxygenation Injury through the Sphingosine Kinase/Sphingosine 1-Phosphate Axis

OBJECTIVE: Experimental and clinical studies have shown that administration of insulin during reperfusion is cardioprotective, but the mechanisms underlying this effect are still unknown. In this study, the ability of insulin to protect apoptotic cardiomyocytes from hypoxia/reoxygenation injury usin...

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Detalles Bibliográficos
Autores principales: Yu, Huan, Che, Xiangxin, Xu, Xiaoyuan, Zheng, Meirong, Zhao, Yong, He, Wei, Yu, Jingmou, Xiong, Jianjun, Li, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859498/
https://www.ncbi.nlm.nih.gov/pubmed/24349009
http://dx.doi.org/10.1371/journal.pone.0080644

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