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Insulin Protects Apoptotic Cardiomyocytes from Hypoxia/Reoxygenation Injury through the Sphingosine Kinase/Sphingosine 1-Phosphate Axis
OBJECTIVE: Experimental and clinical studies have shown that administration of insulin during reperfusion is cardioprotective, but the mechanisms underlying this effect are still unknown. In this study, the ability of insulin to protect apoptotic cardiomyocytes from hypoxia/reoxygenation injury usin...
Autores principales: | Yu, Huan, Che, Xiangxin, Xu, Xiaoyuan, Zheng, Meirong, Zhao, Yong, He, Wei, Yu, Jingmou, Xiong, Jianjun, Li, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859498/ https://www.ncbi.nlm.nih.gov/pubmed/24349009 http://dx.doi.org/10.1371/journal.pone.0080644 |
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