In Silico, In Vitro and In Vivo Analysis of Binding Affinity between N and C-Domains of Clostridium perfringens Alpha Toxin

Clostridium perfringens alpha toxin/phospholipase C (CP-PLC) is one of the most potent bacterial toxins known to cause soft tissue infections like gas gangrene in humans and animals. It is the first bacterial toxin demonstrated to be an enzyme with phospholipase, sphingomyelinase and lecithinase act...

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Detalles Bibliográficos
Autores principales: Uppalapati, Siva Ramakrishna, Kingston, Joseph Jeyabalaji, Qureshi, Insaf Ahmed, Murali, Harishchandra Sripathy, Batra, Harsh Vardhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859591/
https://www.ncbi.nlm.nih.gov/pubmed/24349173
http://dx.doi.org/10.1371/journal.pone.0082024

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