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Elucidating Emergence and Transmission of Multidrug-Resistant Tuberculosis in Treatment Experienced Patients by Whole Genome Sequencing

BACKGROUND: Understanding the emergence and spread of multidrug-resistant tuberculosis (MDR-TB) is crucial for its control. MDR-TB in previously treated patients is generally attributed to the selection of drug resistant mutants during inadequate therapy rather than transmission of a resistant strai...

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Detalles Bibliográficos
Autores principales: Clark, Taane G., Mallard, Kim, Coll, Francesc, Preston, Mark, Assefa, Samuel, Harris, David, Ogwang, Sam, Mumbowa, Francis, Kirenga, Bruce, O’Sullivan, Denise M., Okwera, Alphonse, Eisenach, Kathleen D., Joloba, Moses, Bentley, Stephen D., Ellner, Jerrold J., Parkhill, Julian, Jones-López, Edward C., McNerney, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859632/
https://www.ncbi.nlm.nih.gov/pubmed/24349420
http://dx.doi.org/10.1371/journal.pone.0083012