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Elucidating Emergence and Transmission of Multidrug-Resistant Tuberculosis in Treatment Experienced Patients by Whole Genome Sequencing
BACKGROUND: Understanding the emergence and spread of multidrug-resistant tuberculosis (MDR-TB) is crucial for its control. MDR-TB in previously treated patients is generally attributed to the selection of drug resistant mutants during inadequate therapy rather than transmission of a resistant strai...
Autores principales: | Clark, Taane G., Mallard, Kim, Coll, Francesc, Preston, Mark, Assefa, Samuel, Harris, David, Ogwang, Sam, Mumbowa, Francis, Kirenga, Bruce, O’Sullivan, Denise M., Okwera, Alphonse, Eisenach, Kathleen D., Joloba, Moses, Bentley, Stephen D., Ellner, Jerrold J., Parkhill, Julian, Jones-López, Edward C., McNerney, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859632/ https://www.ncbi.nlm.nih.gov/pubmed/24349420 http://dx.doi.org/10.1371/journal.pone.0083012 |
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