A Trifluoromethyl Analogue of Celecoxib Exerts Beneficial Effects in Neuroinflammation

Celecoxib is a selective cyclooxygenase-2 (COX2) inhibitor. We have previously shown that celecoxib inhibits experimental autoimmune encephalomyelitis (EAE) in COX-2-deficient mice, suggestive for a mode of action involving COX2-independent pathways. In the present study, we tested the effect of a t...

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Detalles Bibliográficos
Autores principales: Di Penta, Alessandra, Chiba, Asako, Alloza, Iraide, Wyssenbach, Ane, Yamamura, Takashi, Villoslada, Pablo, Miyake, Sachiko, Vandenbroeck, Koen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859644/
https://www.ncbi.nlm.nih.gov/pubmed/24349442
http://dx.doi.org/10.1371/journal.pone.0083119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859644/
https://www.ncbi.nlm.nih.gov/pubmed/24349442
http://dx.doi.org/10.1371/journal.pone.0083119

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