A Phenotypic Screen in Zebrafish Identifies a Novel Small-Molecule Inducer of Ectopic Tail Formation Suggestive of Alterations in Non-Canonical Wnt/PCP Signaling

Zebrafish have recently emerged as an attractive model for the in vivo bioassay-guided isolation and characterization of pharmacologically active small molecules of natural origin. We carried out a zebrafish-based phenotypic screen of over 3000 plant-derived secondary metabolite extracts with the go...

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Detalles Bibliográficos
Autores principales: Gebruers, Evelien, Cordero-Maldonado, María Lorena, Gray, Alexander I., Clements, Carol, Harvey, Alan L., Edrada-Ebel, Ruangelie, de Witte, Peter A. M., Crawford, Alexander D., Esguerra, Camila V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859651/
https://www.ncbi.nlm.nih.gov/pubmed/24349481
http://dx.doi.org/10.1371/journal.pone.0083293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859651/
https://www.ncbi.nlm.nih.gov/pubmed/24349481
http://dx.doi.org/10.1371/journal.pone.0083293

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