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High ALK mRNA expression has a negative prognostic significance in rhabdomyosarcoma

BACKGROUND: Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase aberrantly expressed in cancer, but its clinical and functional importance remain controversial. Mutation or amplification of ALK, as well as its expression levels assessed by conventional immunohistochemistry methods, has be...

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Detalles Bibliográficos
Autores principales:	Bonvini, P, Zin, A, Alaggio, R, Pawel, B, Bisogno, G, Rosolen, A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859940/ https://www.ncbi.nlm.nih.gov/pubmed/24149177 http://dx.doi.org/10.1038/bjc.2013.653

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